Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | BRAF | P15056 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Alcohol SCHEMBL6582311 | 0.78 | NPC1 (0.58) | NPC1RAB9AKMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL28891951 | 0.78 | NPC1 (0.41) | NPC1RAB9AKMT2ASMN1; SMN2GAA | |
| SCHEMBL152733 | 0.77 | NUDT1 (0.49) | NPC1RAB9AKMT2ASMN1; SMN2GAA | |
| SCHEMBL1324 | 0.76 | NPC1 (0.62) | NPC1RAB9AKMT2ASMN1; SMN2ALDH1A1 | |
| Bromide SCHEMBL29572453 | 0.76 | NUDT1 (0.48) | NPC1RAB9AKMT2ASMN1; SMN2GAA | |
| Hydrochloric Acid SCHEMBL29571385 | 0.76 | NUDT1 (0.48) | NPC1RAB9AKMT2ASMN1; SMN2GAA | |
| Hydrochloric Acid SCHEMBL6175391 | 0.76 | NUDT1 (0.48) | NPC1RAB9AKMT2ASMN1; SMN2GAA | |
| SCHEMBL19031494 | 0.75 | NPC1 (0.44) | NPC1RAB9AKMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL5790203 | 0.74 | KDM4E (0.43) | NPC1RAB9AKMT2ASMN1; SMN2GAA | |
| SCHEMBL1937210 | 0.74 | RAB9A (0.46) | NPC1RAB9AKMT2ASMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100226985-A1 | VISCOELASTIC AQUEOUS GELS COMPRISING MICROSPHERES | OCTOPLUS SCIENCES B.V. (NL) | 2010-09-09 | — | — | US | disclosed |
| EP-2054039-A2 | VISCOELASTIC AQUEOUS GELS COMPRISING MICROSPHERES | OctoPlus Sciences B.V. (NL) | 2009-05-06 | — | — | EP | disclosed |
| EP-1891941-A1 | Aqueous gels comprising microspheres | OctoPlus Technologies B.V. (NL) | 2008-02-27 | — | — | EP | disclosed |
| WO-2008018796-A2 | VISCOELASTIC AQUEOUS GELS COMPRISING MICROSPHERES | OCTOPLUS SCIENCES B.V. (NL) | 2008-02-14 | — | — | WO | disclosed |