SCHEMBL30826397

SCHEMBL30826397

COc1ccc(C(C)C)c2c1N(C(C)C)CCC2

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.37
TSHR P16473 1/20 0.37
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
KDM4E B2RXH2 2/20 0.34
NPC1 O15118 1/20 0.34
RAB9A P51151 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
C5AR1 P21730 3/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA7 P43166 1/20 0.33
CA9 Q16790 1/20 0.33
ADRA1A P35348 1/20 0.32
HTR2C P28335 1/20 0.31
HTR2B P41595 1/20 0.31
ALOX15 P16050 1/20 0.31
POLB P06746 1/20 0.30
GAA P10253 1/20 0.30
GFER P55789 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29187830 1.00 ALDH1A1 (0.37) ALDH1A1TSHRMEN1KMT2AKDM4E
SCHEMBL29187801 0.85 ALDH1A1 (0.37) ALDH1A1TSHRMEN1KMT2AKDM4E
SCHEMBL30826398 0.85 ALDH1A1 (0.37) ALDH1A1TSHRMEN1KMT2AKDM4E
SCHEMBL21872015 0.74 ADRA1A (0.46) ALDH1A1TSHRMEN1KMT2AKDM4E
SCHEMBL24329609 0.73 C5AR1 (0.31) ALDH1A1TSHRKDM4ENPC1RAB9A
SCHEMBL24316035 0.73 HTR2C (0.44) ALDH1A1MEN1KMT2AHTR2CHTR2B
SCHEMBL24317347 0.70 NOTUM (0.49) HTR2CHTR2B
SCHEMBL19755626 0.69 C5AR1 (0.35) TSHRMEN1KMT2AC5AR1CA1
SCHEMBL19121323 0.67 KMT2A (0.50) ALDH1A1MEN1KMT2AKDM4EHTR2C
SCHEMBL30826400 0.67 PARP1 (0.43) CA1CA2CA7CA9ADRA1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117645562-A Ligand for copper catalytic coupling reaction and application thereof 江西德璟生物科技有限公司 2024-03-05 CN disclosed