Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 5/20 | 0.60 |
| ▸ | AKT1 | P31749 | 4/20 | 0.60 |
| ▸ | MTOR | P42345 | 4/20 | 0.60 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21464208 | 1.00 | PIK3CA (0.60) | PIK3CAAKT1MTORPIK3C3POLB | |
| SCHEMBL30763432 | 0.83 | HTR3A (0.54) | KMT2A | |
| SCHEMBL16037235 | 0.82 | PRMT5 (0.51) | PIK3CACYP1A2MAPTHTTCYP2D6 | |
| SCHEMBL16035866 | 0.80 | CYP1A2 (0.56) | CYP1A2MAPTCYP2D6ALDH1A1CYP3A4 | |
| SCHEMBL4745348 | 0.78 | ALDH1A1 (0.55) | PIK3CAAKT1MTORPIK3C3POLB | |
| SCHEMBL3991610 | 0.77 | CYP1A2 (0.62) | PIK3CAPOLBCYP1A2MAPTHTT | |
| SCHEMBL21464501 | 0.75 | PIK3CA (1.00) | PIK3CAAKT1MTORPIK3C3 | |
| SCHEMBL29922705 | 0.75 | PIK3CA (1.00) | PIK3CAAKT1MTORPIK3C3 | |
| SCHEMBL21464301 | 0.75 | MAPT (0.51) | CYP1A2MAPTHTTCYP2D6ALDH1A1 | |
| SCHEMBL17413516 | 0.75 | LTA4H (0.55) | CYP1A2MAPTHTTCYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112533917-B | Morpholine derivatives as inhibitors of VPS34 | 神经孔疗法股份有限公司 | 2024-06-21 | — | — | CN | disclosed |
| CN-112189012-B | Trisubstituted aryl and heteroaryl derivatives as modulators of PI3 kinase and autophagy pathways | 神经孔疗法股份有限公司 | 2024-02-13 | — | — | CN | disclosed |