SCHEMBL30826985

SCHEMBL30826985

FC(F)(F)Oc1ccc(I)nc1Cl

nearest known ligand 0.36

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
SLC1A5 Q15758 2/20 0.36
KMO O15229 2/20 0.34
PGK1 P00558 1/20 0.33
HCAR1 Q9BXC0 1/20 0.31
NOTUM Q6P988 1/20 0.31
EPHX2 P34913 1/20 0.30
GRIN2B Q13224 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22028866 1.00 SLC1A5 (0.36) SLC1A5KMOPGK1HCAR1NOTUM
SCHEMBL22029205 0.87
SCHEMBL2302384 0.80 SLC1A5 (0.38) SLC1A5KMOPGK1HCAR1NOTUM
SCHEMBL31361182 0.80 SLC1A5 (0.38) SLC1A5KMOPGK1HCAR1NOTUM
SCHEMBL19012130 0.77 SLC1A5 (0.36) SLC1A5KMOPGK1HCAR1
SCHEMBL15574512 0.77 PDE2A (0.31) EPHX2
SCHEMBL24644864 0.77 ALDH1A1 (0.38)
SCHEMBL2306436 0.73 SLC1A5 (0.36) SLC1A5KMOPGK1HCAR1NOTUM
SCHEMBL30894016 0.73 HPGD (0.33)
SCHEMBL19837353 0.73 MBOAT4 (0.40)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119698416-A Imidazo (1, 2-A) pyridine derivatives as RIPK2 inhibitors 英特莱治疗公司 2025-03-25 CN disclosed
CN-118084867-A Condensed ring compound 豪夫迈·罗氏有限公司 2024-05-28 CN disclosed
CN-118084870-A Condensed ring compound 豪夫迈·罗氏有限公司 2024-05-28 CN disclosed
CN-118084866-A Condensed ring compound 豪夫迈·罗氏有限公司 2024-05-28 CN disclosed
CN-118084868-A Condensed ring compound 豪夫迈·罗氏有限公司 2024-05-28 CN disclosed
CN-112105419-B Condensed ring compound 豪夫迈·罗氏有限公司 2024-03-29 CN disclosed