Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK2 | Q05397 | 9/20 | 0.49 |
| ▸ | JAK2 | O60674 | 1/20 | 0.49 |
| ▸ | BRD4 | O60885 | 1/20 | 0.49 |
| ▸ | ACVR1 | Q04771 | 3/20 | 0.48 |
| ▸ | FYN | P06241 | 2/20 | 0.46 |
| ▸ | ACVRL1 | P37023 | 1/20 | 0.46 |
| ▸ | LCK | P06239 | 2/20 | 0.43 |
| ▸ | SRC | P12931 | 2/20 | 0.43 |
| ▸ | HCK | P08631 | 1/20 | 0.43 |
| ▸ | KDR | P35968 | 1/20 | 0.43 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.43 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.43 |
| ▸ | DHFR | P00374 | 1/20 | 0.43 |
| ▸ | FES | P07332 | 1/20 | 0.42 |
| ▸ | RET | P07949 | 1/20 | 0.42 |
| ▸ | ROS1 | P08922 | 1/20 | 0.42 |
| ▸ | CDK4 | P11802 | 1/20 | 0.42 |
| ▸ | JAK1 | P23458 | 1/20 | 0.42 |
| ▸ | TYK2 | P29597 | 1/20 | 0.42 |
| ▸ | JAK3 | P52333 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29213517 | 1.00 | PTK2 (0.49) | PTK2JAK2BRD4ACVR1FYN | |
| SCHEMBL265154 | 0.78 | DHFR (0.59) | FYNLCKSRCHCKKDR | |
| SCHEMBL30560046 | 0.78 | DHFR (0.59) | FYNLCKSRCHCKKDR | |
| SCHEMBL28070389 | 0.78 | HRH4 (0.52) | JAK2BRD4ACVR1FYNLCK | |
| SCHEMBL1674222 | 0.72 | PTK2 (0.63) | PTK2JAK2BRD4FYNLCK | |
| SCHEMBL14994930 | 0.72 | PTK2 (0.49) | PTK2FYNLCKSRCDHFR | |
| SCHEMBL12371236 | 0.71 | JAK2 (0.58) | PTK2JAK2BRD4FYNLCK | |
| SCHEMBL7369256 | 0.70 | HTR2A (0.56) | KDM4EALDH1A1GAAMAPTADRA2C | |
| SCHEMBL1674303 | 0.70 | PTK2 (0.65) | PTK2JAK2BRD4FYNLCK | |
| SCHEMBL29523374 | 0.70 | PTK2 (0.65) | PTK2JAK2BRD4FYNLCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117769427-A | Modified nucleosides and nucleotide analogues as antiviral agents for coronaviruses and other viruses | 埃默里大学 | 2024-03-26 | — | — | CN | disclosed |