Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.63 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.63 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.63 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.63 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.63 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.63 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.63 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.63 |
| ▸ | UQCRB | P14927 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | PKM | P14618 | 2/20 | 0.56 |
| ▸ | USP2 | O75604 | 1/20 | 0.56 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11882161 | 0.85 | ALDH1A1 (0.69) | ALDH1A1KMT2AL3MBTL1CYP3A4MEN1 | |
| SCHEMBL9207324 | 0.85 | ALDH1A1 (0.69) | ALDH1A1KMT2AL3MBTL1CYP3A4CYP2D6 | |
| SCHEMBL14985582 | 0.85 | ALDH1A1 (0.71) | ALDH1A1KMT2AL3MBTL1MEN1POLB | |
| SCHEMBL1990223 | 0.84 | KEAP1 (0.73) | ALDH1A1KMT2AL3MBTL1MEN1SMN1; SMN2 | |
| SCHEMBL16529326 | 0.81 | CYP3A4 (0.56) | ALDH1A1KMT2AL3MBTL1CYP3A4CYP2D6 | |
| SCHEMBL12042479 | 0.80 | ALDH1A1 (0.76) | ALDH1A1KMT2AL3MBTL1CYP3A4UQCRB | |
| SCHEMBL5457170 | 0.80 | ALDH1A1 (0.63) | ALDH1A1KMT2AL3MBTL1MEN1SMN1; SMN2 | |
| SCHEMBL5787822 | 0.80 | KMT2A (0.71) | ALDH1A1KMT2AL3MBTL1CYP3A4CYP2D6 | |
| SCHEMBL5465775 | 0.80 | KMT2A (0.71) | ALDH1A1KMT2AL3MBTL1CYP3A4CYP2D6 | |
| SCHEMBL12228073 | 0.80 | KMT2A (1.00) | ALDH1A1KMT2AL3MBTL1CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240116857-A1 | QUATERNARY AMMONIUM COMPOUNDS AS ANTIMICROBIALS | SAINT LOUIS UNIVERSITY (US) | 2024-04-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240116857-A1 | QUATERNARY AMMONIUM COMPOUNDS AS ANTIMICROBIALS | ABCC1, ARG1, SLC11A2 | ALDH1A1 2841/4885KMT2A 1571/4885L3MBTL1 2234/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.