Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAD52 | P43351 | 1/20 | 0.52 |
| ▸ | BRAF | P15056 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.45 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.45 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.45 |
| ▸ | EGFR | P00533 | 1/20 | 0.45 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.45 |
| ▸ | CDK1 | P06493 | 1/20 | 0.45 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.45 |
| ▸ | CDK2 | P24941 | 1/20 | 0.45 |
| ▸ | SYK | P43405 | 1/20 | 0.45 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.45 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.45 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.45 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7369051 | 0.84 | KMT2A (0.54) | RAD52BRAFALDH1A1CHEK1PDPK1 | |
| SCHEMBL30236 | 0.84 | ALDH1A1 (0.55) | ALDH1A1CYP3A4TDP1TSHRHSD17B10 | |
| SCHEMBL29763986 | 0.84 | ALDH1A1 (0.55) | ALDH1A1CYP3A4TDP1TSHRHSD17B10 | |
| SCHEMBL3796082 | 0.83 | ALDH1A1 (0.61) | ALDH1A1CYP3A4TDP1TSHRHSD17B10 | |
| SCHEMBL29837453 | 0.83 | ALDH1A1 (0.50) | BRAFALDH1A1CYP3A4TDP1TSHR | |
| SCHEMBL1639956 | 0.83 | ALDH1A1 (0.50) | BRAFALDH1A1CYP3A4TDP1TSHR | |
| SCHEMBL23999510 | 0.78 | RAD52 (0.63) | RAD52ALDH1A1CYP3A4TDP1TSHR | |
| SCHEMBL23999865 | 0.77 | ALDH1A1 (0.66) | RAD52ALDH1A1CYP3A4TDP1TSHR | |
| SCHEMBL6155111 | 0.77 | MKNK1 (0.51) | BRAFALDH1A1SYKMKNK2KMT2A | |
| SCHEMBL6157998 | 0.76 | IMPDH2 (0.51) | BRAFALDH1A1CHEK1PDPK1MAP4K4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240116857-A1 | QUATERNARY AMMONIUM COMPOUNDS AS ANTIMICROBIALS | SAINT LOUIS UNIVERSITY (US) | 2024-04-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240116857-A1 | QUATERNARY AMMONIUM COMPOUNDS AS ANTIMICROBIALS | ABCC1, ARG1, SLC11A2 | RAD52 3181/4885BRAF 2853/4885ALDH1A1 2841/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.