Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | KDM1A | O60341 | 2/20 | 0.57 |
| ▸ | MAOA | P21397 | 2/20 | 0.57 |
| ▸ | KDM1B | Q8NB78 | 2/20 | 0.57 |
| ▸ | RCOR1 | Q9UKL0 | 2/20 | 0.57 |
| ▸ | NPC1 | O15118 | 3/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.55 |
| ▸ | FLT3 | P36888 | 12/20 | 0.54 |
| ▸ | NTRK3 | Q16288 | 6/20 | 0.54 |
| ▸ | NTRK2 | Q16620 | 6/20 | 0.54 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.54 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.54 |
| ▸ | NTRK1 | P04629 | 5/20 | 0.53 |
| ▸ | ABL1 | P00519 | 2/20 | 0.53 |
| ▸ | LCK | P06239 | 2/20 | 0.53 |
| ▸ | CSF1R | P07333 | 2/20 | 0.53 |
| ▸ | KIT | P10721 | 2/20 | 0.53 |
| ▸ | BTK | Q06187 | 2/20 | 0.53 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.52 |
| ▸ | PIM1 | P11309 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14980367 | 0.84 | POLB (0.61) | POLBFLT3NTRK3NTRK2NTRK1 | |
| SCHEMBL8251202 | 0.84 | POLB (0.61) | POLBNPC1RAB9AFLT3NTRK3 | |
| SCHEMBL18361298 | 0.83 | HDAC1 (0.71) | FLT3NTRK3NTRK2NTRK1 | |
| SCHEMBL6154880 | 0.83 | POLB (0.59) | POLBKDM1AMAOAKDM1BRCOR1 | |
| Hydrochloric Acid SCHEMBL20592116 | 0.82 | HDAC1 (0.69) | FLT3NTRK3NTRK2NTRK1 | |
| SCHEMBL23448724 | 0.82 | LMNA (0.58) | POLBNPC1FLT3NTRK3NTRK2 | |
| SCHEMBL12020887 | 0.82 | HTR1F (0.69) | CSF1R | |
| SCHEMBL24336470 | 0.81 | FLT3 (0.65) | FLT3NTRK3NTRK2NTRK1ABL1 | |
| SCHEMBL12670070 | 0.81 | POLB (0.56) | POLBNPC1RAB9AFLT3NTRK3 | |
| SCHEMBL12828121 | 0.81 | POLB (0.56) | POLBFLT3NTRK3NTRK2NTRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240116857-A1 | QUATERNARY AMMONIUM COMPOUNDS AS ANTIMICROBIALS | SAINT LOUIS UNIVERSITY (US) | 2024-04-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240116857-A1 | QUATERNARY AMMONIUM COMPOUNDS AS ANTIMICROBIALS | ABCC1, ARG1, SLC11A2 | POLB 1009/4885KDM1A 439/4885MAOA 3409/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.