SCHEMBL30828709

SCHEMBL30828709

Nc1noc2ccc(Cl)cc12

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 2/20 0.50
FAAH O00519 1/20 0.45
LMNA P02545 2/20 0.43
ALOX15 P16050 2/20 0.43
MAPK1 P28482 2/20 0.43
CYP1A2 P05177 1/20 0.43
MAPT P10636 1/20 0.43
THRB P10828 1/20 0.43
AHR P35869 3/20 0.41
ALDH1A1 P00352 5/20 0.41
HPGD P15428 3/20 0.41
HSD17B10 Q99714 2/20 0.41
KDM4E B2RXH2 1/20 0.41
HTR3A P46098 2/20 0.40
KMT2A Q03164 1/20 0.40
GPR55 Q9Y2T6 1/20 0.40
CA12 O43570 1/20 0.39
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
CA3 P07451 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL481909 1.00 IDO1 (0.50) IDO1FAAHLMNAALOX15MAPK1
SCHEMBL482377 0.84 IDO1 (0.47) IDO1LMNAALOX15MAPK1CYP1A2
Hydrochloric Acid SCHEMBL5109377 0.82 IDO1 (0.46) IDO1LMNAALOX15MAPK1CYP1A2
SCHEMBL14919892 0.81 SCN9A (0.45) IDO1LMNAALOX15MAPK1MAPT
SCHEMBL17428656 0.80 MAP4K4 (0.60) KMT2ACYP2C9SCN9A
SCHEMBL6989194 0.79 FAAH (0.51) FAAHLMNAMAPTAHRALDH1A1
SCHEMBL8358457 0.79 NPC1 (0.45) IDO1MAPK1MAPTALDH1A1HPGD
SCHEMBL19075514 0.77 SCN9A (0.44) IDO1FAAHCYP2C9SCN9A
SCHEMBL5513632 0.76 FAAH (0.49) FAAHLMNAMAPTAHRALDH1A1
SCHEMBL1943238 0.76 IDO1 (0.50) IDO1MAPTAHRALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114401960-B Glue degradation agent and using method thereof NOVARTIS AG (CH) 2026-05-26 CN disclosed
EP-4584265-A1 NOVEL COMPOUNDS, COMPOSITIONS AND THERAPEUTIC USES THEREOF Cambridge Enterprise Limited (GB) 2025-07-16 EP disclosed
CN-112334466-B Compounds of formula (I) CTXT私人有限公司 2025-05-30 CN disclosed
WO-2024052690-A1 NOVEL COMPOUNDS, COMPOSITIONS AND THERAPEUTIC USES THEREOF CAMBRIDGE ENTERPRISE LIMITED (GB) 2024-03-14 WO disclosed