Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 3/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.42 |
| ▸ | AHR | P35869 | 1/20 | 0.41 |
| ▸ | HTR3A | P46098 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | NQO1 | P15559 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29793168 | 1.00 | FAAH (0.49) | FAAHALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL1836503 | 0.84 | ALDH1A1 (0.49) | FAAHALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL5508112 | 0.79 | ESR1 (0.63) | ALDH1A1MAPTESR1ESR2HSD17B10 | |
| SCHEMBL6989194 | 0.79 | FAAH (0.51) | FAAHALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL12879280 | 0.76 | ESR1 (0.42) | MAPTESR1ESR2HSP90AA1 | |
| SCHEMBL1759343 | 0.76 | MAPT (0.54) | KMT2AMEN1MAPTESR1ESR2 | |
| SCHEMBL5511112 | 0.76 | ESR1 (0.42) | MAPTESR1ESR2HTR3ATDP1 | |
| SCHEMBL12646518 | 0.76 | FAAH (0.49) | FAAHALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL2708342 | 0.76 | PIM1 (0.49) | ALDH1A1ESR1ESR2TSHRLMNA | |
| SCHEMBL5511923 | 0.76 | ESR1 (0.42) | MAPTESR1ESR2HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240301003-A1 | PLASMIN-RESISTANT PEPTIDES FOR IMPROVED THERAPEUTIC INDEX | NONO INC. (CA) | 2024-09-12 | — | — | US | claimed |
| EP-4274596-A1 | PLASMIN-RESISTANT PEPTIDES FOR IMPROVED THERAPEUTIC INDEX | NoNO Inc. (CA) | 2023-11-15 | — | — | EP | claimed |
| WO-2022150655-A1 | PLASMIN-RESISTANT PEPTIDES FOR IMPROVED THERAPEUTIC INDEX | NONO INC. (CA) | 2022-07-14 | — | — | WO | claimed |
| US-20160206583-A1 | AMINO ACID TREATMENT OF SEIZURES | THE JOHNS HOPKINS UNIVERSITY (US) | 2016-07-21 | — | — | US | claimed |
| WO-2015031493-A1 | AMINO ACID TREATMENT OF SEIZURES | THE JOHNS HOPKINS UNIVERSITY (US) | 2015-03-05 | — | — | WO | claimed |
| CN-102614514-B | GLP-1 acceptor agonists used for treating pains | WANG YONGXIANG | 2014-12-10 | — | — | CN | claimed |
| US-20240301003-A1 | PLASMIN-RESISTANT PEPTIDES FOR IMPROVED THERAPEUTIC INDEX | NONO INC. (CA) | 2024-09-12 | — | — | US | disclosed |
| EP-4274596-A1 | PLASMIN-RESISTANT PEPTIDES FOR IMPROVED THERAPEUTIC INDEX | NoNO Inc. (CA) | 2023-11-15 | — | — | EP | disclosed |
| CN-116897051-A | Plasmin peptides for increasing therapeutic index | 诺诺公司 | 2023-10-17 | — | — | CN | disclosed |
| WO-2022150655-A1 | PLASMIN-RESISTANT PEPTIDES FOR IMPROVED THERAPEUTIC INDEX | NONO INC. (CA) | 2022-07-14 | — | — | WO | disclosed |
| US-20160206583-A1 | AMINO ACID TREATMENT OF SEIZURES | THE JOHNS HOPKINS UNIVERSITY (US) | 2016-07-21 | — | — | US | disclosed |
| WO-2015031493-A1 | AMINO ACID TREATMENT OF SEIZURES | THE JOHNS HOPKINS UNIVERSITY (US) | 2015-03-05 | — | — | WO | disclosed |
| US-8778688-B2 | High-throughput methods for determining pharmacological levels of plasma D-serine | THE JOHNS HOPKINS UNIVERSITY (US) | 2014-07-15 | — | — | US | disclosed |
| CN-1098843-C | Isoxazoles | SANKYO CO (JP) | 2003-01-15 | — | — | CN | disclosed |
| US-6096771-A | ISOXAZOLE DERIVATIVES EXHIBITING EXCELLENT TYPE B AND TYPE A MONOAMINE OXIDASE INHIBITORY ACTIVITIES, THEREFORE USEFUL FOR PREVENTING PARKINSON'S DISEASE, DEPRESSION AND ALZHEIMER'S DISEASE | SANKYO COMPANY, LIMITED (JP) | 2000-08-01 | — | — | US | disclosed |
| US-5965591-A | MONOAMINE OXIDASE INHIBITOR; FOR PROPHYLAXIS AND TREATING PARKINSON'S DISEASE, DEPRESSION AND ALZHEIMER'S DISEASE | SANKYO COMPANY, LIMITED (JP) | 1999-10-12 | — | — | US | disclosed |
| CN-1162957-A | Isoxazole derivatives | SANKYO CO (JP) | 1997-10-22 | — | — | CN | disclosed |
| EP-0779281-A1 | ISOXAZOLES | SANKYO COMPANY LIMITED (JP) | 1997-06-18 | — | — | EP | disclosed |
| US-5578627-A | FOR TREATING CEREBRAL CIRCULATORY DISORDER, HEAD INJURY SEQUELAE AND/OR EPILEPSY | TOYAMA CHEMICAL CO., LTD. (JP) | 1996-11-26 | — | — | US | disclosed |
| EP-0665226-A1 | NOVEL 1,2-BENZISOXAZOLE DERIVATIVE OR SALT THEREOF, AND BRAIN PROTECTIVE AGENT COMPRISING THE SAME | TOYAMA CHEMICAL CO., LTD. (JP) | 1995-08-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240301003-A1 | PLASMIN-RESISTANT PEPTIDES FOR IMPROVED THERAPEUTIC INDEX | DAO, DNPEP, DDO | FAAH 3581/4885ALDH1A1 3618/4885KMT2A 3887/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.