Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 10/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.36 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14722589 | 0.82 | PDE10A (0.43) | PDE10AALDH1A1HPGDPDGFRBPDGFRA | |
| SCHEMBL16838271 | 0.76 | PDE10A (0.55) | PDE10A | |
| SCHEMBL3017328 | 0.75 | PDE10A (0.48) | PDE10A | |
| SCHEMBL145005 | 0.72 | ALDH1A1 (0.55) | MAPTL3MBTL1TDP1MEN1CYP1A2 | |
| SCHEMBL29556850 | 0.72 | ALDH1A1 (0.55) | MAPTL3MBTL1TDP1MEN1CYP1A2 | |
| SCHEMBL15819369 | 0.72 | ALDH1A1 (0.56) | MAPTALDH1A1SMN1; SMN2PDGFRBPDGFRA | |
| SCHEMBL26647275 | 0.72 | P2RX3 (0.41) | PDE10A | |
| SCHEMBL25283172 | 0.71 | ALDH1A1 (0.46) | PDE10AKMT2AALDH1A1SMN1; SMN2PDGFRB | |
| SCHEMBL4419825 | 0.71 | PDE10A (0.59) | PDE10ACYP2D6PDE4DPDE4APDE4B | |
| SCHEMBL6623235 | 0.71 | MAPT (0.45) | MAPTL3MBTL1TDP1MEN1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117794529-A | POLO-like kinase 4 inhibitors | 欧瑞克制药公司 | 2024-03-29 | — | — | CN | disclosed |