Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 9/20 | 0.59 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17439398 | 0.90 | PDK2 (0.64) | PDK2GAAMEN1KMT2APARP1 | |
| SCHEMBL7315127 | 0.85 | PDK2 (0.51) | PDK2GAAMEN1KMT2ASLC6A3 | |
| SCHEMBL7320511 | 0.83 | PDK2 (0.47) | PDK2MEN1KMT2AESR1ESR2 | |
| SCHEMBL7324013 | 0.81 | PDK2 (0.60) | PDK2GAAMEN1KMT2APARP1 | |
| SCHEMBL17456241 | 0.81 | PDK2 (0.52) | PDK2GAAMEN1KMT2APARP1 | |
| SCHEMBL3962635 | 0.80 | PDK2 (0.49) | PDK2GAAMEN1KMT2APARP1 | |
| SCHEMBL13185281 | 0.79 | PDK2 (0.55) | PDK2GAAMEN1KMT2ASLC6A3 | |
| SCHEMBL7315823 | 0.79 | PDK2 (0.61) | PDK2PARP1CA1CA2CA4 | |
| SCHEMBL17471965 | 0.77 | PDK2 (0.47) | PDK2GAAMEN1KMT2AESR1 | |
| SCHEMBL7315657 | 0.77 | PDK2 (0.51) | PDK2GAAMEN1KMT2ASLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160023978-A1 | 6-HYDROXY-2-NAPHTHALENYL FLUORENE DERIVATIVES AND LENS AND CAMERA MODULE USING THE SAME | SAMSUNG ELECTRO-MECHANICS CO., LTD. (KR) | 2016-01-28 | — | — | US | disclosed |
| US-20160023978-A1 | 6-HYDROXY-2-NAPHTHALENYL FLUORENE DERIVATIVES AND LENS AND CAMERA MODULE USING THE SAME | SAMSUNG ELECTRO-MECHANICS CO., LTD. (KR) | 2016-01-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160023978-A1 | 6-HYDROXY-2-NAPHTHALENYL FLUORENE DERIVATIVES AND LENS AND CAMERA MODULE USING THE SAME | SUN2, UACA, HNF4A | PDK2 2562/4885GAA 1762/4885MEN1 541/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.