Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | RORC | P51449 | 4/20 | 0.44 |
| ▸ | PDK2 | Q15119 | 6/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.37 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29660938 | 0.81 | PDK2 (0.41) | L3MBTL1RORCPDK2KDM4EALDH1A1 | |
| SCHEMBL28234906 | 0.77 | PDK2 (0.55) | PDK2KDM4EALDH1A1ALOX15 | |
| SCHEMBL18797724 | 0.73 | PDK2 (0.42) | RORCPDK2 | |
| SCHEMBL2346222 | 0.73 | L3MBTL1 (0.55) | L3MBTL1ALDH1A1MAP2K1ALOX15HTT | |
| SCHEMBL17981528 | 0.72 | RORC (0.51) | RORCPDK2 | |
| SCHEMBL17138413 | 0.71 | L3MBTL1 (0.53) | L3MBTL1RORCKDM4EALDH1A1BRD4 | |
| SCHEMBL17138410 | 0.71 | L3MBTL1 (0.53) | L3MBTL1RORCKDM4EALDH1A1BRD4 | |
| SCHEMBL31471005 | 0.71 | L3MBTL1 (0.53) | L3MBTL1MAP2K1ALOX15HTTTLR7 | |
| SCHEMBL29861782 | 0.71 | L3MBTL1 (0.60) | L3MBTL1KDM4EALDH1A1BRD4MAP2K1 | |
| SCHEMBL108122 | 0.71 | L3MBTL1 (0.60) | L3MBTL1KDM4EALDH1A1BRD4MAP2K1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117777126-A | Imidazopyridines as IRAK4 degradants and uses thereof | 武汉人福创新药物研发中心有限公司 | 2024-03-29 | — | — | CN | disclosed |