Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 5/20 | 0.39 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KDM5A | P29375 | 4/20 | 0.33 |
| ▸ | KDM5B | Q9UGL1 | 4/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.31 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | GLS | O94925 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30829473 | 0.81 | F2 (0.45) | KDM4EMAPTTSHRALDH1A1 | |
| SCHEMBL856957 | 0.73 | POLB (0.52) | GAAKDM4EMAPTROCK1ALDH1A1 | |
| SCHEMBL15130172 | 0.72 | KDM4E (0.42) | KDM4CNAPRTKDM4EMAPTKDM5A | |
| Hydrochloric Acid SCHEMBL11893514 | 0.72 | POLB (0.50) | GAAKDM4EMAPTROCK1ALDH1A1 | |
| SCHEMBL7195355 | 0.69 | POLB (0.49) | KDM4CNAPRTGAAKDM4EMAPT | |
| SCHEMBL23780341 | 0.68 | NAPRT (0.43) | KDM4CNAPRTGAAKDM4EKDM5A | |
| SCHEMBL6663757 | 0.68 | DAO (0.41) | KDM4CKDM4EALDH1A1GLSPOLB | |
| SCHEMBL4666204 | 0.68 | ALKBH2 (0.50) | KDM4CNAPRTKDM4EKDM5AKDM5B | |
| SCHEMBL29912643 | 0.68 | ALKBH2 (0.50) | KDM4CNAPRTKDM4EKDM5AKDM5B | |
| SCHEMBL17793830 | 0.67 | SLC6A7 (0.39) | KDM4CNAPRTKDM4EKDM5AKDM5B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110603254-B | Substituted pyrazole compounds and methods of using the same for treating hyperproliferative diseases | 班塔姆制药有限责任公司 | 2024-04-12 | — | — | CN | disclosed |