SCHEMBL29912643

SCHEMBL29912643

O=C(O)c1ccnn1-c1ccccn1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALKBH2 Q6NS38 1/20 0.50
EGLN1 Q9GZT9 1/20 0.50
KDM5A P29375 5/20 0.46
KDM4C Q9H3R0 5/20 0.46
KDM5B Q9UGL1 5/20 0.46
LMNA P02545 1/20 0.44
NAPRT Q6XQN6 1/20 0.44
P4HTM Q9NXG6 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
KDM2B Q8NHM5 1/20 0.43
OXTR P30559 3/20 0.42
ALDH1A1 P00352 3/20 0.42
AVPR1A P37288 2/20 0.42
HPGD P15428 3/20 0.41
RAB9A P51151 2/20 0.41
NPC1 O15118 1/20 0.41
TP53 P04637 1/20 0.41
KDM4E B2RXH2 3/20 0.40
HSD17B10 Q99714 2/20 0.40
PLK4 O00444 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4666204 1.00 ALKBH2 (0.50) ALKBH2EGLN1KDM5AKDM4CKDM5B
SCHEMBL31569567 0.85 ALDH1A1 (0.46) ALKBH2EGLN1OXTRALDH1A1AVPR1A
SCHEMBL14699189 0.85 OXTR (0.44) ALKBH2EGLN1KDM5AKDM4CKDM5B
SCHEMBL14334137 0.85 FLT3 (0.48) ALKBH2EGLN1KDM5AKDM4CKDM5B
SCHEMBL17793829 0.81 TSHR (0.47) ALKBH2EGLN1KDM5AKDM5BLMNA
SCHEMBL15130172 0.80 KDM4E (0.42) ALKBH2EGLN1KDM5AKDM4CKDM5B
SCHEMBL3101175 0.79 ALKBH2 (0.47) ALKBH2EGLN1KDM5AKDM4CKDM5B
SCHEMBL856957 0.78 POLB (0.52) L3MBTL1ALDH1A1KDM4EROCK1SMN1; SMN2
SCHEMBL17793830 0.78 SLC6A7 (0.39) ALKBH2EGLN1KDM5AKDM4CKDM5B
SCHEMBL23780363 0.78 KDM4E (0.43) ALKBH2EGLN1KDM5AKDM4CKDM5B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115057843-B Preparation method of chlorantraniliprole insecticide 湖南化工研究院有限公司 2024-04-30 CN claimed
CN-115057843-A Preparation method of chlorantraniliprole insecticide 湖南化工研究院有限公司 2022-09-16 CN claimed
US-20250320201-A1 COMPOUNDS AND METHODS USEFUL FOR STABILIZING PHENYLALANINE HYDROXYLASE MUTATIONS AGIOS PHARMACEUTICALS INC (US) 2025-10-16 US disclosed
CN-115057843-A Preparation method of chlorantraniliprole insecticide 湖南化工研究院有限公司 2022-09-16 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250320201-A1 COMPOUNDS AND METHODS USEFUL FOR STABILIZING PHENYLALANINE HYDROXYLASE MUTATIONS PAH, KDM8, PHF8 ALKBH2 313/4885EGLN1 26/4885KDM5A 32/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.