Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 1/20 | 0.51 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.47 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | CA7 | P43166 | 2/20 | 0.46 |
| ▸ | CA9 | Q16790 | 2/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.46 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.46 |
| ▸ | CDC25B | P30305 | 1/20 | 0.45 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.45 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30440820 | 1.00 | MGAM (0.51) | MGAMPDGFRBPDGFRAHSD17B10KDM4E | |
| SCHEMBL2202272 | 1.00 | MGAM (0.51) | MGAMPDGFRBPDGFRAHSD17B10KDM4E | |
| SCHEMBL4404909 | 0.88 | RXFP1 (0.46) | HSD17B10ALDH1A1PDE3BPDE3ASMN1; SMN2 | |
| SCHEMBL19329127 | 0.87 | HPGDS (0.52) | HSD17B10KDM4ESMN1; SMN2L3MBTL1HPGDS | |
| SCHEMBL2201313 | 0.87 | ALPL (0.47) | HSD17B10KDM4EALDH1A1HPGDALOX15 | |
| SCHEMBL4137438 | 0.84 | ACACB (0.44) | PDGFRBPDGFRAHSD17B10KDM4EALDH1A1 | |
| SCHEMBL2199970 | 0.82 | PDGFRB (0.52) | PDGFRBPDGFRAKDM4EALDH1A1HPGD | |
| SCHEMBL2199929 | 0.80 | MRGPRX4 (0.56) | MGAMHPGDMRGPRX4SMN1; SMN2RXRA | |
| SCHEMBL9353615 | 0.80 | MGAM (0.56) | MGAMHSD17B10KDM4EALDH1A1HPGD | |
| SCHEMBL27909234 | 0.78 | PDE10A (0.52) | HSD17B10KDM4EALDH1A1HPGDALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240109915-A1 | NOVEL ACC INHIBITORS | PFIZER INC. (US) | 2024-04-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240109915-A1 | NOVEL ACC INHIBITORS | CBR3, NAT1, ACACB | MGAM 3707/4885PDGFRB 838/4885PDGFRA 959/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.