Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.44 |
| ▸ | HPGDS | O60760 | 1/20 | 0.44 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.44 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.43 |
| ▸ | CSNK1G2 | P78368 | 1/20 | 0.43 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.43 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.43 |
| ▸ | MAP4K5 | Q9Y4K4 | 1/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.42 |
| ▸ | MGLL | Q99685 | 1/20 | 0.42 |
| ▸ | ACACB | O00763 | 1/20 | 0.42 |
| ▸ | ACACA | Q13085 | 1/20 | 0.42 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30829596 | 0.88 | MGAM (0.51) | ALDH1A1SMN1; SMN2HSD17B10L3MBTL1HPGDS | |
| SCHEMBL30440820 | 0.88 | MGAM (0.51) | ALDH1A1SMN1; SMN2HSD17B10L3MBTL1HPGDS | |
| SCHEMBL2202272 | 0.88 | MGAM (0.51) | ALDH1A1SMN1; SMN2HSD17B10L3MBTL1HPGDS | |
| SCHEMBL19329127 | 0.87 | HPGDS (0.52) | SMN1; SMN2HSD17B10L3MBTL1EGFRERBB2 | |
| SCHEMBL2201313 | 0.87 | ALPL (0.47) | ALDH1A1SMN1; SMN2HSD17B10L3MBTL1HPGDS | |
| SCHEMBL4137438 | 0.84 | ACACB (0.44) | ALDH1A1SMN1; SMN2HSD17B10L3MBTL1HPGDS | |
| SCHEMBL2199970 | 0.82 | PDGFRB (0.52) | RXFP1ALDH1A1SMN1; SMN2LMNAMEN1 | |
| SCHEMBL27909233 | 0.79 | ALDH1A1 (0.56) | ALDH1A1PDE10AMTNR1AMTNR1BLMNA | |
| SCHEMBL26317945 | 0.78 | SLC2A1 (0.51) | RXFP1ALDH1A1SMN1; SMN2SRCTGFBR1 | |
| SCHEMBL11152987 | 0.77 | MGAM (0.45) | ALDH1A1SMN1; SMN2MAP4K4CSNK1G2CLK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012056372-A1 | N1/N2-LACTAM ACETYL-CoA CARBOXYLASE INHIBITORS | PFIZER INC. (US) | 2012-05-03 | — | — | WO | disclosed |