Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MYC | P01106 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | XDH | P47989 | 1/20 | 0.40 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.40 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.40 |
| ▸ | TPMT | P51580 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | TTR | P02766 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | RXRA | P19793 | 1/20 | 0.36 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28821494 | 0.81 | TSHR (0.39) | MYCESR1ALOX15PTPN7HSD17B10 | |
| SCHEMBL7926725 | 0.81 | LMNA (0.40) | HSD17B10XDHNR4A1TPMTMEN1 | |
| SCHEMBL7920908 | 0.81 | TTR (0.44) | ALOX15XDHNR4A1TPMTMEN1 | |
| SCHEMBL28265878 | 0.81 | KDM4E (0.35) | ALOX15XDHTSHRKDM4ETUBB4A | |
| SCHEMBL20604827 | 0.80 | CA12 (0.46) | ESR1HSD17B10TSHRTDP1CYP1A2 | |
| SCHEMBL5068332 | 0.79 | CA12 (0.50) | HSD17B10TPMTTTRTSHRALDH1A1 | |
| SCHEMBL30790881 | 0.78 | XDH (0.56) | XDHMEN1KMT2AALDH1A1 | |
| SCHEMBL24448706 | 0.74 | CYP3A4 (0.37) | ESR1ALOX15XDHMEN1KMT2A | |
| SCHEMBL120512 | 0.74 | NOTUM (0.40) | HSD17B10NR4A1TSHRRXRACYP1A2 | |
| SCHEMBL27580039 | 0.74 | MEN1 (0.45) | ALOX15HSD17B10RAPGEF4NR4A1TPMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240109915-A1 | NOVEL ACC INHIBITORS | PFIZER INC. (US) | 2024-04-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240109915-A1 | NOVEL ACC INHIBITORS | CBR3, NAT1, ACACB | MYC 1052/4885ESR1 1556/4885ALOX15 1092/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.