Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | GLA | P06280 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | HSD17B2 | P37059 | 14/20 | 0.45 |
| ▸ | CFTR | P13569 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HSD17B1 | P14061 | 4/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4901202 | 0.88 | KDM4E (0.54) | KDM4EGLAGAAHSD17B2CFTR | |
| SCHEMBL3056728 | 0.87 | KDM4E (0.60) | KDM4EGLAGAAHSD17B2HSD17B1 | |
| SCHEMBL10749314 | 0.82 | KDM4E (0.62) | KDM4EGLAGAAHSD17B2MAPT | |
| SCHEMBL4898591 | 0.82 | KDM4E (0.54) | KDM4EGLAGAAHSD17B2CFTR | |
| SCHEMBL3075472 | 0.82 | KDM4E (0.54) | KDM4EGLAGAAHSD17B2CFTR | |
| SCHEMBL4667356 | 0.80 | HSD17B2 (0.46) | KDM4EHSD17B2HSD17B1 | |
| SCHEMBL3082981 | 0.80 | KDM4E (0.46) | KDM4EGAAHSD17B2HSD17B1 | |
| SCHEMBL3088026 | 0.79 | HSD17B2 (0.45) | KDM4EHSD17B2HSD17B1 | |
| SCHEMBL3081670 | 0.79 | HSD17B2 (0.42) | HSD17B2HSD17B1 | |
| SCHEMBL4667450 | 0.76 | HSD17B2 (0.38) | KDM4EGLAGAAHSD17B2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160150782-A1 | USE OF SELECTED PYRIDONE CARBOXAMIDES OR SALTS THEREOF AS ACTIVE SUBSTANCES AGAINST ABIOTIC PLANT STRESS | BAYER CROPSCIENCE AG (DE) | 2016-06-02 | — | — | US | disclosed |
| US-9102623-B2 | Pyridinecarboxamides, useful-plant-protecting composition comprising them and processes for their preparation and their use | BAYER CROPSCIENCE AG (DE) | 2015-08-11 | — | — | US | disclosed |
| US-20120252670-A1 | PYRIDINECARBOXAMIDES, USEFUL-PLANT-PROTECTING COMPOSITION COMPRISING THEM AND PROCESSES FOR THEIR PREPARATION AND THEIR USE | ZIEMER FRANK (DE) | 2012-10-04 | — | — | US | disclosed |
| US-20080269059-A1 | PYRIDINECARBOXAMIDES, USEFUL-PLANT-PROTECTING COMPOSITION COMPRISING THEM AND PROCESSES FOR THEIR PREPARTION AND THEIR USE | BAYER CROPSCIENCE AG (DE) | 2008-10-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120252670-A1 | PYRIDINECARBOXAMIDES, USEFUL-PLANT-PROTECTING COMPOSITION COMPRISING THEM AND PROCESSES FOR THEIR PREPARATION AND THEIR USE | CYC1, CYCS, CBR3 | KDM4E 740/4885GLA 1905/4885GAA 3433/4885 |
| US-20160150782-A1 | USE OF SELECTED PYRIDONE CARBOXAMIDES OR SALTS THEREOF AS ACTIVE SUBSTANCES AGAINST ABIOTIC PLANT STRESS | PDXK, PLPBP, PNPO | KDM4E 1838/4885GLA 653/4885GAA 1006/4885 |
| US-20080269059-A1 | PYRIDINECARBOXAMIDES, USEFUL-PLANT-PROTECTING COMPOSITION COMPRISING THEM AND PROCESSES FOR THEIR PREPARTION AND THEIR USE | CYC1, PYCR1, CBR3 | KDM4E 826/4885GLA 2012/4885GAA 3296/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.