Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 11/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 11/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 11/20 | 0.36 |
| ▸ | HDAC5 | Q9UQL6 | 5/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31628203 | 0.91 | HDAC1 (0.37) | HDAC1HDAC8HDAC6HDAC5 | |
| SCHEMBL30830306 | 0.84 | — | — | |
| SCHEMBL30830371 | 0.82 | HDAC6 (0.40) | HDAC1HDAC8HDAC6HDAC5 | |
| SCHEMBL31628226 | 0.79 | — | — | |
| SCHEMBL31628087 | 0.76 | F11 (0.31) | — | |
| SCHEMBL31628245 | 0.76 | PLAT (0.32) | — | |
| SCHEMBL30830334 | 0.73 | BACE1 (0.32) | HDAC1 | |
| SCHEMBL31375533 | 0.72 | HDAC6 (0.40) | HDAC1HDAC8HDAC6HDAC5 | |
| SCHEMBL31628392 | 0.72 | HDAC6 (0.40) | HDAC1HDAC8HDAC6HDAC5 | |
| SCHEMBL29797029 | 0.69 | HDAC6 (0.38) | HDAC1HDAC8HDAC6HDAC5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4568958-A1 | BICYCLIC TETRAHYDROTHIAZEPINE DERIVATIVES | F. Hoffmann-La Roche AG (CH) | 2025-06-18 | — | — | EP | disclosed |
| WO-2024033388-A1 | BICYCLIC TETRAHYDROTHIAZEPINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2024-02-15 | — | — | WO | disclosed |