SCHEMBL31628245

SCHEMBL31628245

CC(C)(C)c1nnc(-c2cc3c(cc2F)SC[C@H](OC(N)=O)C(=O)N3)o1

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ PLAT P00750 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30830306 0.91 — —
SCHEMBL31628203 0.83 HDAC1 (0.37) PLAT
SCHEMBL29796810 0.80 GAA (0.36) PLAT
SCHEMBL26961690 0.80 GAA (0.36) PLAT
SCHEMBL29270822 0.77 PLAT (0.30) PLAT
SCHEMBL31628087 0.76 F11 (0.31) —
SCHEMBL30830331 0.76 HDAC1 (0.36) —
SCHEMBL30830334 0.76 BACE1 (0.32) —
SCHEMBL31628145 0.75 HDAC6 (0.31) —
SCHEMBL30675680 0.74 PLAT (0.36) PLAT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4568959-A1 BICYCLIC TETRAHYDROTHIAZEPINE DERIVATIVES F. Hoffmann-La Roche AG (CH) 2025-06-18 — — EP disclosed
Send feedback