Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.40 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.40 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.40 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.40 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.39 |
| ▸ | GRM5 | P41594 | 2/20 | 0.39 |
| ▸ | PTGES | O14684 | 1/20 | 0.39 |
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | CCR5 | P51681 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26641369 | 0.91 | MAOB (0.41) | MAOBGABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL30830765 | 0.89 | PTGER1 (0.43) | PTGER1GRM5SQORL3MBTL1LMNA | |
| SCHEMBL29197676 | 0.85 | GRM5 (0.39) | MAOBGABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL31727224 | 0.84 | PTGES (0.46) | MAOBGABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL31134525 | 0.84 | L3MBTL1 (0.43) | MAOBGABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL24204753 | 0.84 | KDM1A (0.42) | MAOBGABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL31341856 | 0.82 | GRM5 (0.41) | MAOBGABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL25254252 | 0.82 | PTGER1 (0.62) | PTGER1 | |
| SCHEMBL30427588 | 0.82 | MAOA (0.44) | MAOBPTGER1GRM5SQORCYP1A2 | |
| SCHEMBL25191988 | 0.82 | MAOA (0.44) | MAOBPTGER1GRM5SQORCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4581025-A1 | PYRIDAZINON DERIVATIVES AS KAT2 DEGRADERS FOR THE TREATMENT OF PROLIFERATIVE DISORDERS | Auron Therapeutics, Inc. (US) | 2025-07-09 | — | — | EP | disclosed |
| WO-2024050078-A1 | PYRIDAZINON DERIVATIVES AS KAT2 DEGRADERS FOR THE TREATMENT OF PROLIFERATIVE DISORDERS | AURON THERAPEUTICS, INC. (US) | 2024-03-07 | — | — | WO | disclosed |