Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.61 |
| ▸ | TP53 | P04637 | 1/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | KDM6A | O15550 | 1/20 | 0.52 |
| ▸ | KDM4A | O75164 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | KDM5C | P41229 | 1/20 | 0.52 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.52 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.52 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.52 |
| ▸ | COMT | P21964 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | APP | P05067 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18379543 | 0.86 | KDM4E (0.57) | KDM4ETP53CYP2D6HTTSMN1; SMN2 | |
| SCHEMBL13856905 | 0.84 | KDM4E (0.55) | KDM4ETP53CYP2D6HTTSMN1; SMN2 | |
| SCHEMBL9701411 | 0.83 | KDM4E (0.46) | KDM4ETP53CYP2D6HTTSMN1; SMN2 | |
| SCHEMBL3686713 | 0.83 | KDM4E (0.58) | KDM4ETP53CYP2D6HTTSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL8092834 | 0.81 | KDM4E (0.56) | KDM4ETP53CYP2D6HTTSMN1; SMN2 | |
| SCHEMBL8611607 | 0.81 | KDM4E (0.53) | KDM4ETP53CYP2D6HTTSMN1; SMN2 | |
| SCHEMBL9700234 | 0.80 | KDM4E (0.55) | KDM4ETP53CYP2D6HTTSMN1; SMN2 | |
| SCHEMBL9515275 | 0.80 | KDM4E (0.51) | KDM4ETP53CYP2D6HTTSMN1; SMN2 | |
| SCHEMBL8102001 | 0.80 | KDM4E (0.51) | KDM4ETP53CYP2D6HTTSMN1; SMN2 | |
| SCHEMBL5525055 | 0.79 | KDM4E (0.62) | KDM4ETP53CYP2D6HTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118005916-A | Modified polyamino acid derivative with conformational regulating capability, preparation and application thereof | 四川大学 | 2024-05-10 | — | — | CN | claimed |
| CN-118005931-A | Polymer nano material with metal binding capacity and preparation and application thereof | 四川大学 | 2024-05-10 | — | — | CN | claimed |
| WO-1992012131-A1 | 3-HYDROXYPYRIDIN-4-ONE DERIVATIVES AS PHARMACEUTICAL COMPOSITIONS | BRITISH TECHNOLOGY GROUP LIMITED (GB) | 1992-07-23 | — | — | WO | claimed |
| EP-0494754-A1 | 3-hydroxypyridin-4-one derivatives as pharmaceutical compositions | BRITISH TECHNOLOGY GROUP LTD (GB) | 1992-07-15 | — | — | EP | claimed |
| EP-0120669-A2 | Hydroxypyridones, and their pharmaceutical compositions | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1984-10-03 | — | — | EP | claimed |
| CN-118005931-A | Polymer nano material with metal binding capacity and preparation and application thereof | 四川大学 | 2024-05-10 | — | — | CN | disclosed |
| CN-118005916-A | Modified polyamino acid derivative with conformational regulating capability, preparation and application thereof | 四川大学 | 2024-05-10 | — | — | CN | disclosed |
| US-20180338897-A1 | ORAL COMPOSITIONS FOR REDUCING DENTAL STAINS | NEW YORK UNIVERSITY | 2018-11-29 | — | — | US | disclosed |
| US-20150096755-A1 | COMPOSITIONS COMPRISING CARBON DIOXIDE AND REVERSE MICELLES AND METHODS OF USE | NEW YORK UNIVERSITY (US) | 2015-04-09 | — | — | US | disclosed |
| US-20150096755-A1 | COMPOSITIONS COMPRISING CARBON DIOXIDE AND REVERSE MICELLES AND METHODS OF USE | NEW YORK UNIVERSITY (US) | 2015-04-09 | — | — | US | disclosed |
| US-20150096755-A1 | COMPOSITIONS COMPRISING CARBON DIOXIDE AND REVERSE MICELLES AND METHODS OF USE | NEW YORK UNIVERSITY (US) | 2015-04-09 | — | — | US | disclosed |
| EP-2215052-B1 | DESFERRIOXAMINE CONJUGATES, DERIVATIVES AND ANALOGUES | CODD RACHEL (AU) | 2013-07-24 | — | — | EP | disclosed |
| WO-1996022021-A1 | PROTEIN HYDROXYLATION INHIBITORS FOR FIBROPROLIFERATIVE DISORDERS | CORNELL RESEARCH FOUNDATION, INC. (US) | 1996-07-25 | — | — | WO | disclosed |
| WO-1992012131-A1 | 3-HYDROXYPYRIDIN-4-ONE DERIVATIVES AS PHARMACEUTICAL COMPOSITIONS | BRITISH TECHNOLOGY GROUP LIMITED (GB) | 1992-07-23 | — | — | WO | disclosed |
| EP-0494754-A1 | 3-hydroxypyridin-4-one derivatives as pharmaceutical compositions | BRITISH TECHNOLOGY GROUP LTD (GB) | 1992-07-15 | — | — | EP | disclosed |
| EP-0305646-A2 | 3-Hydroxypyrid-4-ones and pharmaceutical compositions | BTG INTERNATIONAL LIMITED (GB) | 1989-03-08 | — | — | EP | disclosed |
| US-4650793-A | NITROGEN-SUBSTITUTED | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1987-03-17 | — | — | US | disclosed |
| US-4585780-A | CHELATION OF HEAVY METALS IN BLOOD | NATIONAL RESEARCH DEVELOPMENT CORP. (GB) | 1986-04-29 | — | — | US | disclosed |
| EP-0120669-A2 | Hydroxypyridones, and their pharmaceutical compositions | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1984-10-03 | — | — | EP | disclosed |
| EP-0120670-A1 | Iron III complexes of hydroxypyridones, and their pharmaceutical compositions | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1984-10-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180338897-A1 | ORAL COMPOSITIONS FOR REDUCING DENTAL STAINS | G6PD, SDHB, SDHA | KDM4E 3168/4885TP53 1683/4885CYP2D6 717/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.