Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRIM24 | O15164 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | GAA | P10253 | 4/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | BCL6 | P41182 | 3/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | APP | P05067 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | SNCA | P37840 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20772684 | 1.00 | TRIM24 (0.51) | TRIM24ALDH1A1SMN1; SMN2TP53HSD17B10 | |
| SCHEMBL20777319 | 0.82 | SMN1; SMN2 (0.54) | TRIM24ALDH1A1SMN1; SMN2TP53HSD17B10 | |
| SCHEMBL24865481 | 0.80 | TRIM24 (0.61) | TRIM24ALDH1A1SMN1; SMN2TP53HSD17B10 | |
| SCHEMBL30832777 | 0.78 | LMNA (0.49) | ALDH1A1SMN1; SMN2TP53HSD17B10MAPT | |
| SCHEMBL20773120 | 0.78 | LMNA (0.49) | ALDH1A1SMN1; SMN2TP53HSD17B10MAPT | |
| SCHEMBL30832794 | 0.78 | BRD4 (0.49) | ALDH1A1SMN1; SMN2TP53HSD17B10MAPT | |
| SCHEMBL20772927 | 0.78 | PKM (0.63) | TRIM24ALDH1A1SMN1; SMN2TP53HSD17B10 | |
| SCHEMBL20772989 | 0.78 | BRD4 (0.49) | ALDH1A1SMN1; SMN2TP53HSD17B10MAPT | |
| SCHEMBL30832833 | 0.78 | PKM (0.63) | TRIM24ALDH1A1SMN1; SMN2TP53HSD17B10 | |
| SCHEMBL20773054 | 0.77 | MEN1 (0.50) | ALDH1A1SMN1; SMN2TP53HSD17B10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111315735-B | Dihydrobenzimidazolone | C4医药公司 | 2024-03-08 | — | — | CN | disclosed |