Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | PARP1 | P09874 | 1/20 | 0.52 |
| ▸ | KLK7 | P49862 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | XDH | P47989 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.48 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.48 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.48 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.48 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.48 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.48 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20777435 | 1.00 | MAPT (0.64) | MAPTKDM4EALDH1A1RAB9APARP1 | |
| SCHEMBL18132580 | 0.82 | MAPT (0.73) | MAPTKDM4EALDH1A1RAB9AKLK7 | |
| SCHEMBL22173221 | 0.79 | MAPT (0.68) | MAPTKDM4EALDH1A1RAB9AKLK7 | |
| SCHEMBL8971238 | 0.78 | ALDH1A1 (0.73) | MAPTKDM4EALDH1A1RAB9APARP1 | |
| SCHEMBL20772671 | 0.77 | MAPT (0.69) | MAPTKDM4EALDH1A1RAB9AKLK7 | |
| SCHEMBL20772536 | 0.77 | MAPT (0.65) | MAPTKDM4EALDH1A1RAB9AKLK7 | |
| SCHEMBL20777365 | 0.76 | MAPT (0.68) | MAPTKDM4EALDH1A1RAB9AKLK7 | |
| SCHEMBL5235008 | 0.75 | ALDH1A1 (0.50) | MAPTKDM4EALDH1A1RAB9APARP1 | |
| SCHEMBL6581654 | 0.75 | KDM4E (0.54) | KDM4EALDH1A1RAB9APARP1KMT2A | |
| SCHEMBL5238436 | 0.75 | TSHR (0.65) | KDM4EALDH1A1KMT2AMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111315735-B | Dihydrobenzimidazolone | C4医药公司 | 2024-03-08 | — | — | CN | disclosed |