Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | BCL2 | P10415 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 8/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8971238 | 0.80 | ALDH1A1 (0.73) | KDM4ELMNASMN1; SMN2BCL2ALDH1A1 | |
| SCHEMBL6580500 | 0.79 | EPHX2 (0.57) | KDM4ELMNASMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL6580082 | 0.78 | BCL2 (0.50) | KDM4ELMNASMN1; SMN2BCL2ALDH1A1 | |
| SCHEMBL6346820 | 0.78 | KMT2A (0.65) | KDM4ESMN1; SMN2ALOX15MEN1KMT2A | |
| SCHEMBL5235008 | 0.77 | ALDH1A1 (0.50) | KDM4ELMNASMN1; SMN2BCL2ALDH1A1 | |
| SCHEMBL16266096 | 0.77 | MEN1 (0.67) | KDM4ELMNASMN1; SMN2BCL2ALDH1A1 | |
| SCHEMBL5238436 | 0.77 | TSHR (0.65) | KDM4ELMNASMN1; SMN2BCL2ALDH1A1 | |
| SCHEMBL1044513 | 0.77 | TSHR (0.58) | KDM4ELMNASMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL6781102 | 0.76 | RAB9A (0.66) | KDM4ELMNASMN1; SMN2ALDH1A1ADRB2 | |
| SCHEMBL5739660 | 0.76 | ALDH1A1 (0.49) | KDM4ELMNASMN1; SMN2BCL2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0716088-B1 | PROCESS FOR PRODUCING 2-(TETRAZOL-5-YL)-4-OXO-4H-BENZOPYRANS | SUMITOMO CHEMICAL CO (JP) | 2004-02-18 | — | — | EP | disclosed |
| US-5597929-A | Production process of 2-(tetrazol-5-yl)-4-oxo-4H-benzopyran | SUMITOMO CHEMICAL CO., LTD. (JP) | 1997-01-28 | — | — | US | disclosed |
| EP-0716088-A1 | PROCESS FOR PRODUCING 2-(TETRAZOL-5-YL)-4-OXO-4H-BENZOPYRANS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1996-06-12 | — | — | EP | disclosed |