Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 2/20 | 0.40 |
| ▸ | ACHE | P22303 | 2/20 | 0.40 |
| ▸ | BACE1 | P56817 | 2/20 | 0.40 |
| ▸ | UBE2M | P61081 | 1/20 | 0.40 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | PDE8B | O95263 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL30201771 | 0.91 | LTA4H (0.53) | LTA4HOPRM1OPRD1CYP3A4MAPT | |
| SCHEMBL9412872 | 0.87 | KDM4E (0.42) | LTA4HKDM4EALDH1A1CYP3A4MAPT | |
| SCHEMBL9412870 | 0.87 | KDM4E (0.42) | LTA4HKDM4EALDH1A1CYP3A4MAPT | |
| SCHEMBL3880869 | 0.82 | DRD2 (0.51) | LTA4HMAPTMEN1KMT2A | |
| SCHEMBL3880873 | 0.82 | DRD2 (0.51) | LTA4HMAPTMEN1KMT2A | |
| SCHEMBL30833222 | 0.82 | DRD2 (0.51) | LTA4HMAPTMEN1KMT2A | |
| SCHEMBL4145169 | 0.81 | LTA4H (0.46) | LTA4HKDM4EALDH1A1CYP3A4MAPT | |
| SCHEMBL6256020 | 0.81 | LTA4H (0.48) | LTA4HKDM4EALDH1A1OPRM1OPRD1 | |
| SCHEMBL3881484 | 0.80 | DRD2 (0.48) | LTA4HKDM4EALDH1A1MAPTMAPK1 | |
| SCHEMBL3881487 | 0.80 | DRD2 (0.48) | LTA4HKDM4EALDH1A1MAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117729914-A | Serotonin 5-HT2B inhibiting compounds | 硕腾服务有限责任公司 | 2024-03-19 | — | — | CN | disclosed |