Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.43 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.42 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | TEAD1 | P28347 | 2/20 | 0.40 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.40 |
| ▸ | TRAP1 | Q12931 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.40 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9413133 | 0.87 | KDM4E (0.42) | LTA4HKDM4EALDH1A1HSD11B1HCRTR1 | |
| SCHEMBL6153609 | 0.82 | DRD2 (0.50) | LTA4HALDH1A1DRD2 | |
| SCHEMBL30833207 | 0.81 | LTA4H (0.48) | LTA4HKDM4EALDH1A1HSD11B1CYP3A4 | |
| SCHEMBL17562365 | 0.79 | KMT2A (0.55) | ALDH1A1MAPTSIGMAR1 | |
| SCHEMBL1427493 | 0.79 | OPRM1 (0.39) | KDM4EALDH1A1CHRM5ACHESIGMAR1 | |
| SCHEMBL14780037 | 0.79 | AR (0.41) | — | |
| SCHEMBL719296 | 0.78 | CHRM2 (0.53) | ALDH1A1CHRM5SIGMAR1 | |
| SCHEMBL29691892 | 0.78 | CHRM2 (0.53) | ALDH1A1CHRM5SIGMAR1 | |
| SCHEMBL19364501 | 0.78 | CHRM2 (0.53) | ALDH1A1CHRM5SIGMAR1 | |
| SCHEMBL707808 | 0.78 | CHRM2 (0.53) | ALDH1A1CHRM5SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090082389-A1 | PESTICIDAL SUBSTITUTED PIPERIDINES | MERIAL LIMITED | 2009-03-26 | — | — | US | disclosed |
| EP-1692939-A1 | Pesticidal substituted piperidines | Bayer CropScience S.A. (FR) | 2006-08-23 | — | — | EP | disclosed |
| WO-2005058317-A1 | GLYCINE TRANSPORTER-1 INHIBIRORS | GLAXO GROUP LIMITED (GB) | 2005-06-30 | — | — | WO | disclosed |
| WO-2005058317-A1 | GLYCINE TRANSPORTER-1 INHIBIRORS | GLAXO GROUP LIMITED (GB) | 2005-06-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090082389-A1 | PESTICIDAL SUBSTITUTED PIPERIDINES | PIR, ACHE, PREP | LTA4H 811/4885KDM4E 1025/4885ALDH1A1 262/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.