Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 13/20 | 0.58 |
| ▸ | OPRK1 | P41145 | 10/20 | 0.58 |
| ▸ | KCNH2 | Q12809 | 9/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 8/20 | 0.41 |
| ▸ | NOS3 | P29474 | 1/20 | 0.40 |
| ▸ | NOS1 | P29475 | 1/20 | 0.40 |
| ▸ | NOS2 | P35228 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30833216 | 0.83 | KCNH2 (0.58) | OPRM1OPRK1KCNH2OPRD1 | |
| SCHEMBL30833229 | 0.83 | OPRK1 (0.39) | OPRM1OPRK1KCNH2OPRD1 | |
| SCHEMBL30833218 | 0.82 | OPRK1 (0.39) | OPRM1OPRK1KCNH2CYP2D6OPRD1 | |
| SCHEMBL30833209 | 0.82 | OPRK1 (0.56) | OPRM1OPRK1KCNH2OPRD1 | |
| SCHEMBL30833223 | 0.81 | OPRK1 (0.39) | OPRM1OPRK1KCNH2OPRD1 | |
| SCHEMBL30833198 | 0.81 | OPRK1 (0.47) | OPRM1OPRK1KCNH2OPRD1 | |
| SCHEMBL30833231 | 0.80 | OPRK1 (0.39) | OPRM1OPRK1KCNH2OPRD1 | |
| SCHEMBL30833213 | 0.80 | OPRK1 (0.48) | OPRM1OPRK1KCNH2OPRD1 | |
| SCHEMBL30833224 | 0.79 | OPRK1 (0.59) | OPRM1OPRK1KCNH2OPRD1 | |
| SCHEMBL30344212 | 0.78 | HTR1A (0.46) | OPRM1OPRK1SMN1; SMN2OPRD1NOS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117729914-A | Serotonin 5-HT2B inhibiting compounds | 硕腾服务有限责任公司 | 2024-03-19 | — | — | CN | disclosed |