Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 17/20 | 0.58 |
| ▸ | OPRK1 | P41145 | 15/20 | 0.58 |
| ▸ | OPRM1 | P35372 | 9/20 | 0.58 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30833198 | 0.90 | OPRK1 (0.47) | KCNH2OPRK1OPRM1OPRD1 | |
| SCHEMBL30833209 | 0.89 | OPRK1 (0.56) | KCNH2OPRK1OPRM1OPRD1 | |
| SCHEMBL30833213 | 0.89 | OPRK1 (0.48) | KCNH2OPRK1OPRM1OPRD1 | |
| SCHEMBL30833238 | 0.88 | OPRK1 (0.59) | KCNH2OPRK1OPRM1OPRD1 | |
| SCHEMBL30833227 | 0.87 | OPRM1 (0.48) | KCNH2OPRK1OPRM1OPRD1 | |
| SCHEMBL30833224 | 0.85 | OPRK1 (0.59) | KCNH2OPRK1OPRM1OPRD1 | |
| SCHEMBL30833220 | 0.83 | OPRM1 (0.58) | KCNH2OPRK1OPRM1OPRD1 | |
| SCHEMBL30833232 | 0.83 | ROCK2 (0.41) | KCNH2OPRK1OPRM1OPRD1 | |
| SCHEMBL30833214 | 0.82 | OPRK1 (0.59) | KCNH2OPRK1OPRM1OPRD1 | |
| SCHEMBL30344212 | 0.81 | HTR1A (0.46) | OPRK1OPRM1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117729914-A | Serotonin 5-HT2B inhibiting compounds | 硕腾服务有限责任公司 | 2024-03-19 | — | — | CN | disclosed |