Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRIM24 | O15164 | 1/20 | 0.36 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.35 |
| ▸ | BMPR1B | O00238 | 4/20 | 0.32 |
| ▸ | BMPR1A | P36894 | 4/20 | 0.32 |
| ▸ | ACVRL1 | P37023 | 4/20 | 0.32 |
| ▸ | ACVR1 | Q04771 | 4/20 | 0.32 |
| ▸ | TGFBR1 | P36897 | 3/20 | 0.32 |
| ▸ | CDC25A | P30304 | 1/20 | 0.32 |
| ▸ | CDC25B | P30305 | 1/20 | 0.32 |
| ▸ | CDC25C | P30307 | 1/20 | 0.32 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.31 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.31 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.31 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.31 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.31 |
| ▸ | CD38 | P28907 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29769797 | 0.67 | CD38 (0.35) | CD38 | |
| SCHEMBL29769801 | 0.64 | TRIM24 (0.40) | TRIM24BMPR1BBMPR1AACVRL1ACVR1 | |
| SCHEMBL30261739 | 0.62 | TBXAS1 (0.35) | TBXAS1CD38 | |
| SCHEMBL29764153 | 0.61 | TRIM24 (0.40) | TRIM24BMPR1BBMPR1AACVRL1ACVR1 | |
| SCHEMBL21831489 | 0.61 | TRIM24 (0.40) | TRIM24BMPR1BBMPR1AACVRL1ACVR1 | |
| SCHEMBL29769804 | 0.61 | CD38 (0.44) | TBXAS1CD38 | |
| SCHEMBL12945553 | 0.60 | CD38 (0.35) | TBXAS1CD38 | |
| SCHEMBL12364215 | 0.59 | ACVRL1 (0.46) | TRIM24BMPR1BBMPR1AACVRL1ACVR1 | |
| SCHEMBL23564216 | 0.58 | TRIM24 (0.37) | TRIM24BMPR1BBMPR1AACVRL1ACVR1 | |
| SCHEMBL30540203 | 0.58 | S100A4 (0.41) | CD38 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4284511-B1 | AZAQUINOLINES AS INHIBITORS OF CD38 | BOEHRINGER INGELHEIM INT (DE) | 2025-07-16 | — | — | EP | disclosed |
| US-20240279224-A1 | QUINOLINES AND AZAQUINOLINES AS INHIBITORS OF CD38 | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2024-08-22 | — | — | US | disclosed |
| CN-117580829-A | Quinoline and azaquinolines as inhibitors of CD38 | 勃林格英格翰国际有限公司 | 2024-02-20 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240279224-A1 | QUINOLINES AND AZAQUINOLINES AS INHIBITORS OF CD38 | CD38, NQO1, NQO2 | TRIM24 3511/4885TBXAS1 2337/4885BMPR1B 4679/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.