Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | METAP1 | P53582 | 2/20 | 0.35 |
| ▸ | METAP2 | P50579 | 1/20 | 0.35 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.34 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | NOS3 | P29474 | 1/20 | 0.33 |
| ▸ | NOS1 | P29475 | 1/20 | 0.33 |
| ▸ | NOS2 | P35228 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | GMNN | O75496 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26179657 | 0.80 | NOS2 (0.48) | MKNK1MKNK2PIK3CANOS3NOS1 | |
| SCHEMBL10262761 | 0.79 | BRAF (0.45) | TDP1MKNK1MKNK2NOS3NOS1 | |
| SCHEMBL7281511 | 0.76 | PDE3B (0.41) | L3MBTL1TSHRLMNAMAPTSMN1; SMN2 | |
| SCHEMBL27728631 | 0.73 | DHODH (0.38) | CYP19A1CYP1A2TP53NFKB1CCR1 | |
| SCHEMBL30948977 | 0.73 | HCRTR1 (0.39) | — | |
| SCHEMBL15243522 | 0.72 | KDM4E (0.47) | TDP1METAP1CYP1A2CYP3A4TSHR | |
| SCHEMBL27941864 | 0.72 | MKNK1 (0.56) | TDP1MKNK1MKNK2NOS3NOS1 | |
| SCHEMBL27662888 | 0.71 | USP7 (0.41) | MAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL30948975 | 0.71 | NR1H2 (0.34) | L3MBTL1NPSR1KDM4ELMNAMAPT | |
| SCHEMBL31646940 | 0.71 | BRD4 (0.43) | L3MBTL1BRD4KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4620955-A1 | MC4R ANTAGONIST COMPOUND, PHARMACEUTICAL COMPOSITION AND PHARMACEUTICAL USE THEREOF | Changchun Genescience Pharmaceutical Co., Ltd. (CN) | 2025-09-24 | — | — | EP | disclosed |
| CN-120202199-A | MC4R antagonist compound, pharmaceutical composition and application thereof in medicine | 长春金赛药业有限责任公司 | 2025-06-24 | — | — | CN | disclosed |
| CN-117736206-A | Urea derivatives as MC4R antagonists, pharmaceutical compositions and pharmaceutical applications thereof | 长春金赛药业有限责任公司 | 2024-03-22 | — | — | CN | disclosed |