Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 2/20 | 0.34 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | NMT1 | P30419 | 1/20 | 0.32 |
| ▸ | AXL | P30530 | 3/20 | 0.30 |
| ▸ | TDP2 | O95551 | 2/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.30 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | RAF1 | P04049 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31634725 | 0.80 | MC4R (0.37) | NR1H2NR1H3 | |
| SCHEMBL30996534 | 0.75 | EPHX2 (0.37) | NPC1RAB9AKDM4EALDH1A1MAPT | |
| SCHEMBL30948977 | 0.75 | HCRTR1 (0.39) | AXL | |
| SCHEMBL10941382 | 0.74 | HSD11B1 (0.50) | NR1H2NR1H3NPC1RAB9AALDH1A1 | |
| SCHEMBL30948973 | 0.69 | METAP2 (0.32) | — | |
| SCHEMBL31646940 | 0.69 | BRD4 (0.43) | NPC1RAB9AKDM4ELMNAL3MBTL1 | |
| SCHEMBL7281511 | 0.67 | PDE3B (0.41) | NPC1RAB9AMEN1LMNAMAPT | |
| SCHEMBL10939995 | 0.67 | NPC1 (0.41) | NR1H2NR1H3NPC1RAB9ATDP2 | |
| SCHEMBL27662888 | 0.66 | USP7 (0.41) | MEN1ALDH1A1POLBMAPTHPGD | |
| SCHEMBL11996732 | 0.64 | TDP2 (0.53) | NR1H2NR1H3NPC1RAB9ATDP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4620955-A1 | MC4R ANTAGONIST COMPOUND, PHARMACEUTICAL COMPOSITION AND PHARMACEUTICAL USE THEREOF | Changchun Genescience Pharmaceutical Co., Ltd. (CN) | 2025-09-24 | — | — | EP | disclosed |
| CN-120202199-A | MC4R antagonist compound, pharmaceutical composition and application thereof in medicine | 长春金赛药业有限责任公司 | 2025-06-24 | — | — | CN | disclosed |
| WO-2024104452-A1 | MC4R ANTAGONIST COMPOUND, PHARMACEUTICAL COMPOSITION AND PHARMACEUTICAL USE THEREOF | 长春金赛药业有限责任公司 | 2024-05-23 | — | — | WO | disclosed |