Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 6/20 | 0.39 |
| ▸ | HCRTR2 | O43614 | 6/20 | 0.39 |
| ▸ | MC4R | P32245 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
| ▸ | AXL | P30530 | 2/20 | 0.31 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.30 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.30 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30948975 | 0.75 | NR1H2 (0.34) | AXL | |
| SCHEMBL30996534 | 0.73 | EPHX2 (0.37) | PPARA | |
| SCHEMBL30833320 | 0.73 | TDP1 (0.37) | — | |
| SCHEMBL23837827 | 0.70 | IDO1 (0.41) | HCRTR1HCRTR2 | |
| SCHEMBL25435848 | 0.70 | LRRK2 (0.41) | HCRTR1HCRTR2 | |
| SCHEMBL2276312 | 0.69 | CHRNB2 (0.43) | PPARA | |
| SCHEMBL31634725 | 0.69 | MC4R (0.37) | MC4R | |
| SCHEMBL20969942 | 0.69 | PPARA (0.40) | PPARAGABRG2GABRB3GABRA5 | |
| SCHEMBL12331975 | 0.68 | PPARA (0.37) | HCRTR1HCRTR2PPARA | |
| SCHEMBL31646940 | 0.68 | BRD4 (0.43) | HCRTR1HCRTR2MC4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4620955-A1 | MC4R ANTAGONIST COMPOUND, PHARMACEUTICAL COMPOSITION AND PHARMACEUTICAL USE THEREOF | Changchun Genescience Pharmaceutical Co., Ltd. (CN) | 2025-09-24 | — | — | EP | disclosed |
| CN-120202199-A | MC4R antagonist compound, pharmaceutical composition and application thereof in medicine | 长春金赛药业有限责任公司 | 2025-06-24 | — | — | CN | disclosed |
| WO-2024104452-A1 | MC4R ANTAGONIST COMPOUND, PHARMACEUTICAL COMPOSITION AND PHARMACEUTICAL USE THEREOF | 长春金赛药业有限责任公司 | 2024-05-23 | — | — | WO | disclosed |