Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BPTF | Q12830 | 1/20 | 0.39 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.38 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.38 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | PIM1 | P11309 | 1/20 | 0.37 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.37 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.37 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.37 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.37 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.37 |
| ▸ | AR | P10275 | 2/20 | 0.36 |
| ▸ | SCD | O00767 | 3/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL30833353 | 0.93 | AR (0.38) | LMNAHTTARSCD | |
| SCHEMBL27169500 | 0.86 | MEN1 (0.43) | ARSCDDCTPP1 | |
| SCHEMBL30349708 | 0.83 | LMNA (0.43) | LMNAHTTSCDDCTPP1KDM1A | |
| SCHEMBL29942240 | 0.83 | BPTF (0.54) | BPTFHTT | |
| SCHEMBL22565347 | 0.82 | PRKAA2 (0.47) | ARCHRM4 | |
| SCHEMBL30460341 | 0.81 | BPTF (0.41) | BPTFLMNAHTT | |
| Trifluoroacetic Acid SCHEMBL30054159 | 0.80 | SCD (0.42) | ARSCDDCTPP1 | |
| SCHEMBL31753620 | 0.77 | DCTPP1 (0.43) | LMNAHTTSCDDCTPP1KDM1A | |
| SCHEMBL24267252 | 0.76 | SCD (0.33) | ARSCD | |
| SCHEMBL31589862 | 0.74 | PARP1 (0.37) | ARDCTPP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117580839-A | Anti-cancer nuclear hormone receptor targeting compounds | 诺维逊生物股份有限公司 | 2024-02-20 | — | — | CN | disclosed |