SCHEMBL31753620

SCHEMBL31753620

C#CCC1CCN(c2ccc(C(N)=O)nn2)CC1

nearest known ligand 0.54

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
DCTPP1 Q9H773 2/20 0.43
LMNA P02545 1/20 0.42
HTT P42858 1/20 0.42
SCD O00767 4/20 0.39
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
KDM1A O60341 1/20 0.37
MAOB P27338 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30349708 0.84 LMNA (0.43) DCTPP1LMNAHTTSCDMEN1
SCHEMBL31753239 0.83 LMNA (0.45) DCTPP1LMNAHTTSCDMEN1
SCHEMBL31752219 0.80 HRH3 (0.48) LMNAKMT2ASMN1; SMN2KDM1AMAOB
SCHEMBL31747278 0.79 KDM1A (0.55) LMNAKMT2AKDM1AMAOB
SCHEMBL30833344 0.77 BPTF (0.39) DCTPP1LMNAHTTSCDKDM1A
SCHEMBL30588284 0.76 LMNA (0.43) LMNAHTTSCDMEN1KMT2A
SCHEMBL11636961 0.76 CYP1A2 (0.49) LMNAHTTMEN1KMT2A
SCHEMBL11635317 0.74 CYP1A2 (0.51) HTT
SCHEMBL5182925 0.72 SCD (0.60) SCDMEN1KMT2ASMN1; SMN2
SCHEMBL62904 0.72 PARP1 (0.49) HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025262297-A1 PROTAC DEGRADERS OF MLLT1 AND/OR MLLT3 DARK BLUE THERAPEUTICS LTD (GB) 2025-12-26 WO disclosed