Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE8B | O95263 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 4/20 | 0.38 |
| ▸ | ATM | Q13315 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | CPT1A | P50416 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30833476 | 0.88 | PDE8B (0.43) | PDE8BALDH1A1NPSR1LMNAMAPT | |
| SCHEMBL30833440 | 0.87 | GAA (0.40) | PDE8BALDH1A1NPSR1LMNAMAPT | |
| SCHEMBL30833501 | 0.86 | PDE8B (0.38) | PDE8BALDH1A1NPSR1LMNAMAPT | |
| SCHEMBL30833510 | 0.78 | PDE8B (0.40) | PDE8BALDH1A1NPSR1LMNAKDM1A | |
| SCHEMBL29082018 | 0.77 | ALDH1A1 (0.42) | ALDH1A1NPSR1LMNAMAPTTSHR | |
| SCHEMBL5180568 | 0.76 | KDM1A (0.48) | PDE8BALDH1A1LMNAKDM1ATSHR | |
| SCHEMBL30833475 | 0.75 | PDE8B (0.39) | PDE8BALDH1A1NPSR1LMNAMAPT | |
| SCHEMBL30833484 | 0.75 | PDE8B (0.39) | PDE8BALDH1A1NPSR1LMNAMAPT | |
| SCHEMBL29423917 | 0.74 | PDE8B (0.45) | PDE8BALDH1A1KDM1ATSHRATM | |
| SCHEMBL30833435 | 0.74 | PDE8B (0.38) | PDE8BALDH1A1NPSR1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118164961-A | 4-Methylsulfonyl substituted piperidine urea compounds for the treatment of Dilated Cardiomyopathy (DCM) | 迈奥卡迪亚公司 | 2024-06-11 | — | — | CN | disclosed |
| CN-111393414-B | 4-Methylsulfonyl substituted piperidine urea compounds for the treatment of Dilated Cardiomyopathy (DCM) | 迈奥卡迪亚公司 | 2024-05-07 | — | — | CN | disclosed |