Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | CPT1A | P50416 | 3/20 | 0.39 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.39 |
| ▸ | WDR77 | Q9BQA1 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | CPT2 | P23786 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25322738 | 0.83 | PRMT5 (0.34) | ALDH1A1NPSR1LMNAMAPTPRMT5 | |
| SCHEMBL25322740 | 0.83 | PRMT5 (0.34) | ALDH1A1NPSR1LMNAMAPTPRMT5 | |
| SCHEMBL18685698 | 0.78 | KDM4E (0.52) | MAPTKMT2AHTT | |
| SCHEMBL18403342 | 0.77 | SLC34A1 (0.44) | ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL30833402 | 0.77 | PDE8B (0.40) | ALDH1A1NPSR1LMNAMAPTCPT1A | |
| SCHEMBL30833510 | 0.76 | PDE8B (0.40) | ALDH1A1NPSR1LMNACPT1APRMT5 | |
| SCHEMBL9254476 | 0.76 | CHRNB2 (0.51) | ALDH1A1NPSR1LMNAMAPTCPT1A | |
| SCHEMBL24632464 | 0.75 | ALDH1A1 (0.44) | ALDH1A1NPSR1LMNAMAPTL3MBTL1 | |
| SCHEMBL30833508 | 0.75 | WNT3 (0.36) | NPSR1LMNACPT1AL3MBTL1MEN1 | |
| SCHEMBL20202192 | 0.75 | PRMT5 (0.50) | ALDH1A1NPSR1LMNAMAPTPRMT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116568677-A | piperidin-1-yl-N-pyridin-3-yl-2-oxoacetamide derivatives useful for the treatment of MTAP deficiency and/or MTA accumulating cancers | 探戈医药股份有限公司 | 2023-08-08 | — | — | CN | disclosed |