Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 4/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | KIF18A | Q8NI77 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30833511 | 0.84 | TSHR (0.47) | RORCTSHRUSP2KMT2ACYP2C9 | |
| SCHEMBL17942474 | 0.84 | TSHR (0.47) | RORCTSHRUSP2KMT2ACYP2C9 | |
| SCHEMBL30833383 | 0.79 | MEN1 (0.42) | RORCTSHRUSP2MEN1KMT2A | |
| SCHEMBL30833449 | 0.78 | RORC (0.42) | RORCTSHRUSP2MEN1KMT2A | |
| SCHEMBL17949037 | 0.78 | TSHR (0.47) | RORCTSHRUSP2CYP2C9CYP2D6 | |
| SCHEMBL29530615 | 0.78 | TSHR (0.47) | RORCTSHRUSP2CYP2C9CYP2D6 | |
| SCHEMBL29529765 | 0.78 | TSHR (0.49) | RORCTSHRUSP2KMT2ACYP2C9 | |
| SCHEMBL17949438 | 0.78 | TSHR (0.49) | RORCTSHRUSP2KMT2ACYP2C9 | |
| SCHEMBL30833483 | 0.77 | RIPK1 (0.42) | RORCMEN1KMT2A | |
| Trifluoroacetic Acid SCHEMBL30833404 | 0.74 | RORC (0.40) | RORCTSHRUSP2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118164961-A | 4-Methylsulfonyl substituted piperidine urea compounds for the treatment of Dilated Cardiomyopathy (DCM) | 迈奥卡迪亚公司 | 2024-06-11 | — | — | CN | disclosed |
| CN-111393414-B | 4-Methylsulfonyl substituted piperidine urea compounds for the treatment of Dilated Cardiomyopathy (DCM) | 迈奥卡迪亚公司 | 2024-05-07 | — | — | CN | disclosed |