Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | GPR119 | Q8TDV5 | 9/20 | 0.44 |
| ▸ | MMP13 | P45452 | 1/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.37 |
| ▸ | STS | P08842 | 1/20 | 0.37 |
| ▸ | WNT3 | P56703 | 2/20 | 0.36 |
| ▸ | SFRP1 | Q8N474 | 2/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.36 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30833444 | 0.92 | MEN1 (0.45) | MEN1KMT2AGPR119MMP13TRPV1 | |
| SCHEMBL17942528 | 0.82 | GPR119 (0.55) | GPR119MMP13STS | |
| SCHEMBL30833514 | 0.80 | GPR119 (0.44) | MEN1KMT2AGPR119MMP13TRPV1 | |
| SCHEMBL30833410 | 0.79 | GPR119 (0.45) | MEN1KMT2AGPR119MMP13TRPV1 | |
| SCHEMBL30833412 | 0.74 | GPR119 (0.42) | MEN1KMT2AGPR119MMP13TRPV1 | |
| SCHEMBL30833473 | 0.74 | GPR119 (0.42) | MEN1KMT2AGPR119MMP13TRPV1 | |
| SCHEMBL30833502 | 0.74 | MEN1 (0.42) | MEN1KMT2ATRPV1STSWNT3 | |
| SCHEMBL17949423 | 0.73 | GPR119 (0.54) | GPR119MMP13PIK3CD | |
| SCHEMBL30833482 | 0.72 | MEN1 (0.40) | MEN1KMT2AWNT3SFRP1NR1H2 | |
| SCHEMBL17942310 | 0.72 | MMP13 (0.41) | MEN1KMT2AGPR119MMP13PIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118164961-A | 4-Methylsulfonyl substituted piperidine urea compounds for the treatment of Dilated Cardiomyopathy (DCM) | 迈奥卡迪亚公司 | 2024-06-11 | — | — | CN | disclosed |
| CN-111393414-B | 4-Methylsulfonyl substituted piperidine urea compounds for the treatment of Dilated Cardiomyopathy (DCM) | 迈奥卡迪亚公司 | 2024-05-07 | — | — | CN | disclosed |