Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | WNT3 | P56703 | 2/20 | 0.34 |
| ▸ | SFRP1 | Q8N474 | 2/20 | 0.34 |
| ▸ | IRAK4 | Q9NWZ3 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.32 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | PDE8B | O95263 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30833382 | 0.86 | SFRP1 (0.38) | MEN1KMT2AWNT3SFRP1NPC1 | |
| SCHEMBL17948872 | 0.81 | STS (0.42) | — | |
| SCHEMBL17948870 | 0.81 | STS (0.42) | — | |
| SCHEMBL17948869 | 0.81 | STS (0.42) | — | |
| SCHEMBL30833457 | 0.81 | MEN1 (0.35) | MEN1KMT2AWNT3SFRP1L3MBTL1 | |
| SCHEMBL30833399 | 0.80 | MEN1 (0.38) | MEN1KMT2AWNT3SFRP1NPC1 | |
| SCHEMBL30833453 | 0.79 | WNT3 (0.38) | MEN1KMT2AWNT3SFRP1NR1H2 | |
| SCHEMBL30833506 | 0.76 | SFRP1 (0.39) | MEN1KMT2AWNT3SFRP1NR1H2 | |
| SCHEMBL18025949 | 0.76 | IRAK4 (0.35) | KMT2AIRAK4 | |
| SCHEMBL17942469 | 0.74 | KMT2A (0.34) | KMT2AIRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118164961-A | 4-Methylsulfonyl substituted piperidine urea compounds for the treatment of Dilated Cardiomyopathy (DCM) | 迈奥卡迪亚公司 | 2024-06-11 | — | — | CN | disclosed |
| CN-111393414-B | 4-Methylsulfonyl substituted piperidine urea compounds for the treatment of Dilated Cardiomyopathy (DCM) | 迈奥卡迪亚公司 | 2024-05-07 | — | — | CN | disclosed |