Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WNT3 | P56703 | 2/20 | 0.38 |
| ▸ | SFRP1 | Q8N474 | 2/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.37 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | RORC | P51449 | 1/20 | 0.36 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | STS | P08842 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30833382 | 0.93 | SFRP1 (0.38) | WNT3SFRP1NR1H2NR1H3MEN1 | |
| SCHEMBL30833474 | 0.82 | KDM1A (0.39) | WNT3SFRP1MEN1KMT2AALDH1A1 | |
| SCHEMBL17948997 | 0.81 | STS (0.44) | SFRP1MEN1KMT2AMAPTSTS | |
| SCHEMBL30833454 | 0.81 | KMT2A (0.40) | WNT3SFRP1NR1H2NR1H3HSD11B1 | |
| SCHEMBL30833493 | 0.79 | MEN1 (0.38) | WNT3SFRP1NR1H2NR1H3MEN1 | |
| SCHEMBL17949425 | 0.77 | STS (0.46) | SFRP1MEN1KMT2AMAPTSTS | |
| SCHEMBL17942546 | 0.74 | TGFBR1 (0.44) | STS | |
| SCHEMBL17942437 | 0.74 | CYP3A4 (0.39) | KMT2ARORCLMNAGRIA2 | |
| SCHEMBL30833506 | 0.74 | SFRP1 (0.39) | WNT3SFRP1NR1H2NR1H3MEN1 | |
| SCHEMBL30833484 | 0.74 | PDE8B (0.39) | MEN1KMT2AMAPTNPSR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118164961-A | 4-Methylsulfonyl substituted piperidine urea compounds for the treatment of Dilated Cardiomyopathy (DCM) | 迈奥卡迪亚公司 | 2024-06-11 | — | — | CN | disclosed |
| CN-111393414-B | 4-Methylsulfonyl substituted piperidine urea compounds for the treatment of Dilated Cardiomyopathy (DCM) | 迈奥卡迪亚公司 | 2024-05-07 | — | — | CN | disclosed |