Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP3 | Q9NY33 | 5/20 | 0.63 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.51 |
| ▸ | NTSR2 | O95665 | 1/20 | 0.51 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.51 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.51 |
| ▸ | CCKBR | P32239 | 1/20 | 0.49 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.49 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.49 |
| ▸ | ITGAL | P20701 | 1/20 | 0.49 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.49 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.49 |
| ▸ | KISS1R | Q969F8 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30833604 | 1.00 | DPP3 (0.63) | DPP3OPRM1SLC6A2NTSR2NTSR1 | |
| SCHEMBL29772690 | 0.90 | DPP3 (0.64) | DPP3OPRM1SLC6A2NTSR2NTSR1 | |
| SCHEMBL29772689 | 0.90 | DPP3 (0.64) | DPP3OPRM1SLC6A2NTSR2NTSR1 | |
| SCHEMBL30424046 | 0.87 | DPP3 (0.67) | DPP3OPRM1SLC6A2 | |
| SCHEMBL30288104 | 0.86 | DPP3 (0.71) | DPP3OPRM1SLC6A2NTSR2NTSR1 | |
| SCHEMBL29772691 | 0.85 | DPP3 (0.63) | DPP3OPRM1SLC6A2OPRD1OPRK1 | |
| SCHEMBL30052255 | 0.85 | DPP3 (0.69) | DPP3OPRM1ITGB2ICAM1ITGAL | |
| SCHEMBL29572021 | 0.85 | DPP3 (0.71) | DPP3SLC6A2NTSR2NTSR1SORT1 | |
| SCHEMBL30051395 | 0.84 | DPP3 (0.59) | DPP3OPRM1 | |
| SCHEMBL30610091 | 0.83 | DPP3 (0.69) | DPP3OPRM1NTSR2NTSR1SORT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240109936-A1 | NOVEL MACROCYCLIC OPIOID PEPTIDES | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2024-04-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240109936-A1 | NOVEL MACROCYCLIC OPIOID PEPTIDES | OPRL1, OPRM1, OPRK1 | DPP3 673/4885OPRM1 2/4885SLC6A2 1171/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.