Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 14/20 | 0.52 |
| ▸ | JAK2 | O60674 | 1/20 | 0.44 |
| ▸ | JAK3 | P52333 | 1/20 | 0.44 |
| ▸ | FLT3 | P36888 | 2/20 | 0.44 |
| ▸ | BTK | Q06187 | 2/20 | 0.44 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.43 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.43 |
| ▸ | SRC | P12931 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30833713 | 0.91 | AXL (0.52) | EGFRFLT3ALKFGFR1SRC | |
| SCHEMBL30833720 | 0.88 | AXL (0.52) | EGFRFLT3ALKFGFR1SRC | |
| SCHEMBL30833735 | 0.86 | EGFR (0.52) | EGFRJAK2JAK3FLT3BTK | |
| SCHEMBL29190583 | 0.86 | EGFR (0.59) | EGFRJAK2JAK3FLT3ALK | |
| SCHEMBL30833786 | 0.83 | EGFR (0.48) | EGFRJAK2JAK3FLT3BTK | |
| SCHEMBL30833734 | 0.80 | ALK (0.49) | EGFRJAK2JAK3FLT3BTK | |
| SCHEMBL30833637 | 0.77 | MAP3K7 (0.53) | EGFRFLT3ALKFGFR1SRC | |
| SCHEMBL30833742 | 0.76 | IGF1R (0.43) | EGFRJAK2JAK3FLT3BTK | |
| SCHEMBL30833660 | 0.76 | ALK (0.43) | EGFRJAK2JAK3FLT3BTK | |
| SCHEMBL29190637 | 0.76 | ALK (0.65) | EGFRFLT3ALKFGFR1SRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113896744-B | Selective EGFR inhibitor | 成都先导药物开发股份有限公司 | 2024-04-16 | — | — | CN | disclosed |