Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | ACHE | P22303 | 2/20 | 0.43 |
| ▸ | PTGDR2 | Q9Y5Y4 | 5/20 | 0.42 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.40 |
| ▸ | APP | P05067 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3353132 | 0.85 | MAPT (0.44) | MAPTPTGDR2LMNAALDH1A1TSHR | |
| SCHEMBL3352848 | 0.80 | MAPT (0.51) | MAPTPTGDR2LMNAALDH1A1 | |
| SCHEMBL3357241 | 0.80 | ACHE (0.41) | MAPTACHESIRT6APPBCHE | |
| SCHEMBL3354484 | 0.80 | ALDH1A1 (0.41) | MAPTACHESIRT6LMNAHIF1A | |
| SCHEMBL25766155 | 0.79 | PTGDR2 (0.55) | PTGDR2SCN5ASCN9A | |
| SCHEMBL3358219 | 0.79 | HTR1D (0.43) | MAPTPTGDR2ALDH1A1TDP1SCN5A | |
| SCHEMBL31434242 | 0.79 | PTGDR2 (0.55) | PTGDR2SCN5ASCN9A | |
| SCHEMBL3349054 | 0.78 | PTGDR2 (0.44) | MAPTACHEPTGDR2LMNAALDH1A1 | |
| SCHEMBL3355435 | 0.78 | ALDH1A1 (0.42) | MAPTACHESIRT6APPBCHE | |
| SCHEMBL3354240 | 0.78 | HTR7 (0.45) | MAPTACHESIRT6HIF1AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2141163-A1 | Substituted thiazolidinones, their production and utilisation as medicine | Bayer Schering Pharma AG (DE) | 2010-01-06 | — | — | EP | disclosed |
| EP-2141163-A1 | Substituted thiazolidinones, their production and utilisation as medicine | Bayer Schering Pharma AG (DE) | 2010-01-06 | — | — | EP | disclosed |