Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGF1R | P08069 | 5/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | BCR | P11274 | 1/20 | 0.36 |
| ▸ | ZAP70 | P43403 | 1/20 | 0.34 |
| ▸ | MAPK8 | P45983 | 3/20 | 0.33 |
| ▸ | EGFR | P00533 | 2/20 | 0.33 |
| ▸ | CDK19 | Q9BWU1 | 1/20 | 0.33 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.33 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.32 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | AURKA | O14965 | 2/20 | 0.31 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.30 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30833707 | 0.84 | ALK (0.40) | IGF1RKMT2AMEN1ZAP70EGFR | |
| SCHEMBL30833628 | 0.81 | IGF1R (0.46) | IGF1RKMT2AMEN1MAPK8CDK19 | |
| SCHEMBL30833652 | 0.80 | IGF1R (0.40) | IGF1RKMT2AMEN1ABL1BCR | |
| SCHEMBL30833673 | 0.76 | SYK (0.45) | ZAP70MAPK8EGFRCDK19ALK | |
| SCHEMBL5912776 | 0.76 | ALDH1A1 (0.41) | KMT2AMEN1ABL1BCRALDH1A1 | |
| SCHEMBL30833745 | 0.74 | AURKA (0.43) | IGF1RKMT2AMAPK8ALKMAPK9 | |
| SCHEMBL29190615 | 0.74 | GLO1 (0.43) | IGF1RKMT2AMEN1ABL1BCR | |
| SCHEMBL22500906 | 0.74 | ABL1 (0.47) | IGF1RKMT2AMEN1ABL1BCR | |
| SCHEMBL29389889 | 0.74 | ABL1 (0.47) | IGF1RKMT2AMEN1ABL1BCR | |
| SCHEMBL25056307 | 0.70 | MEN1 (0.52) | IGF1RKMT2AMEN1MAPK8CDK19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113896744-B | Selective EGFR inhibitor | 成都先导药物开发股份有限公司 | 2024-04-16 | — | — | CN | disclosed |