Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGF1R | P08069 | 12/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | NTRK1 | P04629 | 3/20 | 0.39 |
| ▸ | MAPK8 | P45983 | 3/20 | 0.38 |
| ▸ | CDK19 | Q9BWU1 | 1/20 | 0.37 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.37 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.36 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30833627 | 0.88 | BCL6 (0.39) | IGF1RMAPK8ALKMAPK9MAPK10 | |
| SCHEMBL30833745 | 0.85 | AURKA (0.43) | IGF1RKMT2ANTRK1MAPK8ALK | |
| SCHEMBL30833645 | 0.85 | PIN1 (0.36) | IGF1RMEN1KMT2AMAPTPIN1 | |
| SCHEMBL30833663 | 0.85 | PIN1 (0.36) | IGF1RMEN1KMT2AMAPTPIN1 | |
| SCHEMBL30833754 | 0.85 | MAPT (0.36) | IGF1RMEN1KMT2AMAPTPIN1 | |
| SCHEMBL25056307 | 0.83 | MEN1 (0.52) | IGF1RMEN1KMT2AMAPK8CDK19 | |
| SCHEMBL30833638 | 0.82 | PTK2 (0.45) | IGF1RNTRK1 | |
| SCHEMBL30833726 | 0.81 | IGF1R (0.40) | IGF1RMEN1KMT2AMAPK8CDK19 | |
| SCHEMBL17544600 | 0.81 | IGF1R (0.51) | IGF1RMEN1KMT2ANTRK1MAPK8 | |
| SCHEMBL30088390 | 0.81 | IGF1R (0.51) | IGF1RMEN1KMT2ANTRK1MAPK8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113896744-B | Selective EGFR inhibitor | 成都先导药物开发股份有限公司 | 2024-04-16 | — | — | CN | disclosed |