Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ULK1 | O75385 | 3/20 | 0.47 |
| ▸ | PTK2 | Q05397 | 2/20 | 0.43 |
| ▸ | MAPK3 | P27361 | 10/20 | 0.43 |
| ▸ | CDC7 | O00311 | 1/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.41 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.41 |
| ▸ | PIM1 | P11309 | 1/20 | 0.41 |
| ▸ | PRKACA | P17612 | 1/20 | 0.41 |
| ▸ | CDK7 | P50613 | 1/20 | 0.41 |
| ▸ | CDK9 | P50750 | 1/20 | 0.41 |
| ▸ | HIPK2 | Q9H2X6 | 1/20 | 0.41 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.41 |
| ▸ | CDK1 | P06493 | 1/20 | 0.41 |
| ▸ | CDK4 | P11802 | 1/20 | 0.41 |
| ▸ | CDK2 | P24941 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 2/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.38 |
| ▸ | TYK2 | P29597 | 1/20 | 0.38 |
| ▸ | JAK3 | P52333 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24179306 | 0.84 | MAPK3 (0.44) | MAPK3 | |
| SCHEMBL29137455 | 0.83 | ULK1 (0.42) | ULK1PTK2MAPK3CDC7ROCK2 | |
| SCHEMBL30631756 | 0.83 | ULK1 (0.42) | ULK1PTK2MAPK3CDC7ROCK2 | |
| SCHEMBL25530155 | 0.83 | AURKA (0.47) | PTK2CDC7MAP4K4IRAK4CDK1 | |
| SCHEMBL29761996 | 0.82 | CCNA2 (0.43) | ULK1MAPK3CDK9CDK2JAK2 | |
| SCHEMBL30833778 | 0.82 | CCNA2 (0.43) | ULK1MAPK3CDK9CDK2JAK2 | |
| SCHEMBL15600758 | 0.82 | CCNA2 (0.43) | ULK1MAPK3CDK9CDK2JAK2 | |
| SCHEMBL22520101 | 0.81 | LRRK2 (0.38) | MAPK3CDK9CDK2IGF1R | |
| SCHEMBL24716006 | 0.81 | ULK1 (0.48) | ULK1PTK2MAPK3CDC7ROCK2 | |
| SCHEMBL21557746 | 0.80 | IGF1R (0.51) | CDC7ROCK2MAP4K4PIM1PRKACA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105330698-B | Loop coil aryl phosphorous oxides and sulfide | 齐鲁制药有限公司 | 2019-05-28 | — | — | CN | disclosed |