Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 16/20 | 0.60 |
| ▸ | IL1B | P01584 | 4/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.41 |
| ▸ | CCNK | O75909 | 1/20 | 0.41 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.41 |
| ▸ | CDK2 | P24941 | 1/20 | 0.41 |
| ▸ | CDK9 | P50750 | 1/20 | 0.41 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30834001 | 0.91 | NLRP3 (0.62) | NLRP3IL1B | |
| SCHEMBL30054103 | 0.91 | NLRP3 (0.73) | NLRP3IL1BKCNH2CCNT1CCNK | |
| SCHEMBL27204014 | 0.91 | NLRP3 (0.73) | NLRP3IL1BKCNH2CCNT1CCNK | |
| SCHEMBL25864811 | 0.90 | NLRP3 (0.52) | NLRP3IL1B | |
| SCHEMBL29030549 | 0.90 | NLRP3 (0.52) | NLRP3IL1B | |
| SCHEMBL30833987 | 0.89 | NLRP3 (0.56) | NLRP3IL1BKCNH2CCNT1CCNK | |
| SCHEMBL25303354 | 0.88 | IL1B (0.52) | NLRP3IL1B | |
| SCHEMBL30488555 | 0.88 | IL1B (0.52) | NLRP3IL1B | |
| SCHEMBL25303351 | 0.88 | IL1B (0.52) | NLRP3IL1B | |
| SCHEMBL25303114 | 0.87 | NLRP3 (0.51) | NLRP3IL1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117986258-A | NLRP3 inflammation corpuscle inhibitor and application thereof | 药捷安康(南京)科技股份有限公司 | 2024-05-07 | — | — | CN | disclosed |