Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 8/20 | 0.45 |
| ▸ | IL1B | P01584 | 2/20 | 0.38 |
| ▸ | SMYD3 | Q9H7B4 | 2/20 | 0.35 |
| ▸ | HTR1A | P08908 | 2/20 | 0.33 |
| ▸ | ROCK2 | O75116 | 4/20 | 0.33 |
| ▸ | ROCK1 | Q13464 | 3/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | HRH1 | P35367 | 1/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30833989 | 0.86 | CAMK2D (0.40) | NLRP3IL1BROCK2ROCK1 | |
| SCHEMBL25302097 | 0.82 | KAT2B (0.39) | NLRP3IL1B | |
| SCHEMBL25302099 | 0.82 | KAT2B (0.39) | NLRP3IL1B | |
| SCHEMBL30833928 | 0.76 | KAT2B (0.33) | NLRP3 | |
| SCHEMBL27292457 | 0.75 | NLRP3 (0.55) | NLRP3IL1BROCK2ROCK1 | |
| SCHEMBL30834019 | 0.74 | NLRP3 (0.49) | NLRP3IL1BROCK2 | |
| SCHEMBL30488557 | 0.72 | BTK (0.49) | KMT2A | |
| SCHEMBL31039762 | 0.69 | NLRP3 (0.56) | NLRP3IL1BROCK2ROCK1 | |
| SCHEMBL25294691 | 0.69 | CCNT1 (0.41) | — | |
| SCHEMBL25294690 | 0.69 | CCNT1 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4613749-A1 | NLRP3 INFLAMMASOME INHIBITOR AND USE THEREOF | TransThera Sciences (Nanjing), Inc. (CN) | 2025-09-10 | — | — | EP | disclosed |
| CN-117986258-A | NLRP3 inflammation corpuscle inhibitor and application thereof | 药捷安康(南京)科技股份有限公司 | 2024-05-07 | — | — | CN | disclosed |